Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.
about
E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repressionReciprocal regulation of p53 and malic enzymes modulates metabolism and senescencep53 opens the mitochondrial permeability transition pore to trigger necrosisComprehensive molecular characterization of human colon and rectal cancerMechanisms of ferroptosisNeurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator.FOXO transcription factors: key regulators of cellular quality controlThe quiescent cellular state is Arf/p53-dependent and associated with H2AX downregulation and genome stabilityTumor suppressor p53 and its gain-of-function mutants in cancerTumor suppressor p53 and its mutants in cancer metabolismOxidative stress and pulmonary fibrosisAnother fork in the road--life or death decisions by the tumour suppressor p53p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stressTP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse modelMolecular pathogenesis of sporadic colorectal cancersThe role of the p53 tumor suppressor in metabolism and diabetesp53 Acetylation: Regulation and ConsequencesDexamethasone reduces sensitivity to cisplatin by blunting p53-dependent cellular senescence in non-small cell lung cancerMammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrityAn extra copy of p53 suppresses development of spontaneous Kras-driven but not radiation-induced cancerThe p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humansConvergence and divergence between the transcriptional responses to Zika virus infection and prenatal irradiationMisfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Cancer: A piece of the p53 puzzle.Ferroptosis: A missing puzzle piece in the p53 blueprint?Essential role for centromeric factors following p53 loss and oncogenic transformationTargeting tumor suppressor networks for cancer therapeutics.The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expressionClinical update on cancer: molecular oncology of head and neck cancerChemosensitivity and p53; new tricks by an old dogMacrophage infiltration and genetic landscape of undifferentiated uterine sarcomas.Dependence of p53-deficient cells on the DHX9 DExH-box helicase.PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.Downmodulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4(+) T cell responsesA vicious partnership between AKT and PHLDA3 to facilitate neuroendocrine tumors.Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells.Ferroptosis as a p53-mediated activity during tumour suppressionLow levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells.p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis
P2860
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P2860
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Distinct p53 transcriptional p ...... sponses and tumor suppression.
@ast
Distinct p53 transcriptional p ...... sponses and tumor suppression.
@en
type
label
Distinct p53 transcriptional p ...... sponses and tumor suppression.
@ast
Distinct p53 transcriptional p ...... sponses and tumor suppression.
@en
prefLabel
Distinct p53 transcriptional p ...... sponses and tumor suppression.
@ast
Distinct p53 transcriptional p ...... sponses and tumor suppression.
@en
P2093
P2860
P1433
P1476
Distinct p53 transcriptional p ...... sponses and tumor suppression.
@en
P2093
Anthony N Karnezis
Colleen A Brady
Dadi Jiang
Daniela Kenzelmann Broz
Eunice J Park
Laura D Attardi
Lesley A Jarvis
Margaret E McLaughlin
Margaret M Kozak
Shashwati Basak
P2860
P304
P356
10.1016/J.CELL.2011.03.035
P407
P577
2011-05-01T00:00:00Z