The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
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Ribosomal Antibiotics: Contemporary ChallengesInvestigation of cationicity and structure of pseudin-2 analogues for enhanced bacterial selectivity and anti-inflammatory activity.Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis.Optimization of oncocin for antibacterial activity using a SPOT synthesis approach: extending the pathogen spectrum to Staphylococcus aureus.Host defense antimicrobial peptides as antibiotics: design and application strategies.Proline-rich antimicrobial peptides targeting protein synthesis.CAMPR3: a database on sequences, structures and signatures of antimicrobial peptides.A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli.Suppression of the toxicity of Bac7 (1-35), a bovine peptide antibiotic, and its production in E. coli.Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.Leveraging family-specific signatures for AMP discovery and high-throughput annotationIn vivo Efficacy and Pharmacokinetics of Optimized Apidaecin Analogs.Mechanistic and structural basis of bioengineered bovine Cathelicidin-5 with optimized therapeutic activity.Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.Insect-derived short proline-rich and murine cathelicidin-related antimicrobial peptides act synergistically on Gram-negative bacteria in vitro.Cell-penetrating peptides with intracellular organelle targeting.Dual effect of chloramphenicol peptides on ribosome inhibition.Bacterial Protein Synthesis as a Target for Antibiotic Inhibition.Ribosomal binding and antibacterial activity of ethylene glycol-bridged apidaecin Api137 and oncocin Onc112 conjugates.The Mechanism of Killing by the Proline-Rich Peptide Bac7(1-35) against Clinical Strains of Pseudomonas aeruginosa Differs from That against Other Gram-Negative BacteriaShort Proline-Rich Antimicrobial Peptides Inhibit Either the Bacterial 70S Ribosome or the Assembly of its Large 50S Subunit.Pharmacokinetics and in vivo efficacy of optimized oncocin derivatives.Protein aggregation as an antibiotic design strategy.The Effect of Selective D- or Nα-Methyl Arginine Substitution on the Activity of the Proline-Rich Antimicrobial Peptide, Chex1-Arg20.Antimicrobial peptides targeting bacterial ribosome.Antimicrobial peptides target ribosomes.Proline-rich antimicrobial peptides show a long-lasting post-antibiotic effect on Enterobacteriaceae and Pseudomonas aeruginosa.Mechanism of actions of Oncocin, a proline-rich antimicrobial peptide, in early elongation revealed by single-molecule FRET.C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide.An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.Spiroplasma affects host aphid proteomics feeding on two nutritional resources.Correlating uptake and activity of proline-rich antimicrobial peptides in Escherichia coli.T-cell regulation through a basic suppressive mechanism targeting low-density lipoprotein receptor-related protein 1.Methods for Elucidating the Mechanism of Action of Proline-Rich and Other Non-lytic Antimicrobial Peptides.The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics.Analysis of the antimicrobial mechanism of porcine beta defensin 2 against E. coli by electron microscopy and differentially expressed genes
P2860
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P2860
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
@ast
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
@en
type
label
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
@ast
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
@en
prefLabel
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
@ast
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
@en
P2093
P2860
P356
P1476
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
@en
P2093
Ivan B Lomakin
Raktim N Roy
Thomas A Steitz
P2860
P2888
P304
P356
10.1038/NSMB.3031
P577
2015-05-18T00:00:00Z