Regulation of the B cell receptor repertoire and self-reactivity by BAFF - Wikidata - wikimedia - TriplyDB

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

http://www.wikidata.org/entity/Q35686885

about

Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens Recent advances in understanding and treating vasculitis Factors regulating immunoglobulin production by normal and disease-associated plasma cells The promise and challenge of high-throughput sequencing of the antibody repertoire.Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.Current and emerging treatment options for ANCA-associated vasculitis: potential role of belimumab and other BAFF/APRIL targeting agents.Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape DNA vaccine molecular adjuvants SP-D-BAFF and SP-D-APRIL enhance anti-gp120 immune response and increase HIV-1 neutralizing antibody titers BAFF/APRIL inhibition decreases selection of naive but not antigen-induced autoreactive B cells in murine systemic lupus erythematosus The discovery and development of belimumab: the anti-BLyS-lupus connection Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing.BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses.Novel treatments for systemic lupus erythematosus.B Cell-Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease.The Yaa locus and IFN-α fine-tune germinal center B cell selection in murine systemic lupus erythematosus HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity In vivo VL-targeted microbial superantigen induced global shifts in the B cell repertoire.Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease.Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance.Targeting the splicing of mRNA in autoimmune diseases: BAFF inhibition in Sjögren's syndrome as a proof of concept Spotlight on blisibimod and its potential in the treatment of systemic lupus erythematosus: evidence to date Targeting BAFF in autoimmunity.BAFF and selection of autoreactive B cells Treatment of primary Sjögren's syndrome with anti-CD20 therapy (rituximab). A feasible approach or just a starting point?Biologic differences between various inhibitors of the BLyS/BAFF pathway: should we expect differences between belimumab and other inhibitors in development?Belimumab therapy in systemic lupus erythematosus.Monoclonal antibody treatments for rheumatoid arthritis.Future prospects in biologic therapy for systemic lupus erythematosus.Therapeutic targeting of the BAFF/APRIL axis in systemic lupus erythematosus.Trials and Tribulations with VH Replacement.B cells biology in systemic lupus erythematosus-from bench to bedside.Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells.B Cell-Activating Factor as a New Potential Marker in Inflammatory Bowel Disease.DNA-reactive B cells in lupus.B-cell-activating factor and autoimmune myasthenia gravis.Checkpoints for Autoreactive B Cells in the Peripheral Blood of Lupus Patients Assessed by Flow Cytometry.Clinical significance of autoantibodies in a large cohort of patients with chronic graft-versus-host disease defined by NIH criteria.

P2860

Q24626603-09153833-3A13-4976-9EF5-FB2A68E789D7 Q26747046-67B5574C-CA05-4210-A263-561F2193B709 Q27021855-61BBDB33-D99E-4D9A-82C9-099EC55A0129 Q33962293-55B5B1E4-24C1-4B3F-A2E4-218CE79BB2C5 Q34681437-22BA6868-C475-48C7-9151-333037CF00C4 Q34960458-C6EE6755-201D-496A-8DB9-255DAA5F2344 Q35058903-3A55CDC6-B0EF-4F07-ABEB-0137915F070B Q35452032-27EF33AB-B315-4122-AD24-90ABDA1172C6 Q35582239-09196436-0575-4B4B-82C8-0BD77055F51F Q35640984-084836D1-6181-4FAC-9DC6-258AD9A5DAD3 Q35686772-8CE5F91A-37D5-4710-A9BA-20C67A60E6AD Q35691272-B975D013-756B-48B9-8A5B-9E6058E974EE Q35784452-AFF3ECFF-1755-41B4-9D45-461B8E2406AF Q36016522-FDB4F1A1-9847-428B-B3E9-A2EFEC016733 Q36059553-940D38D3-0F85-40D5-A096-96A3D0F38000 Q36128542-F2C5B82F-C893-4B47-9A8E-9EF7AC82535B Q36339344-4B830BB5-8263-45CE-BAC2-2E3E4915351B Q36345558-8DC0B619-71C9-4845-B561-930BD6B32306 Q36547706-1B79B92E-2F9C-4FAE-84D2-B0B1830DE2CB Q36687539-BDAB403E-DA6F-48DE-9915-12DFCA656672 Q37017346-7D5DF0FD-0B8B-463B-856D-0FBEDB1852E3 Q37387660-19D73EA9-2CD7-4648-8FA9-1C9540267A4E Q37696041-404B2E65-5DDC-44EE-9C2F-5E5A7E488832 Q37709763-39C55F4F-E265-4176-BD67-98711E6465D1 Q37802627-30183844-94A8-4034-9D48-93F8B9C37780 Q37900758-A0967C6C-2008-4CBB-B436-AEEEE5E3DA39 Q37912214-AA0D4ABD-A85A-4226-B747-603FC0AA73E3 Q38006643-5C2B252B-AB95-473E-92F9-0A9937BF93C6 Q38097328-E964BFB8-02EA-4506-8C79-16AAC0985379 Q38116065-A15DB718-9A3F-4CE7-B41D-39DC1B43E63F Q38135706-72078CC6-3F18-4058-B97B-B2F0E5B5F683 Q38187489-3957D199-3899-4F31-B601-7272E8B3BF9F Q38187652-9A7039FC-BCCE-4547-A011-DEE472237DA5 Q38631964-714A80A5-FAAB-412B-A124-B3871E93A51E Q38714538-96809F39-1FF3-4F4A-AD6F-30B854587C4C Q38884402-0ACBB997-792E-4103-B8B9-A82AE0F66CFE Q38922669-11A5C618-CB7D-483E-A755-007C8A2E73CF Q40179681-DBDBF1C1-88F1-42EC-B7A0-AA5558A00409 Q41103048-8ED17407-757C-4F24-A524-175A060970BE Q41180891-638DB03F-6D75-4945-92E1-8332E4C2B9EA

P2860

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

http://www.wikidata.org/entity/Q35686885

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

@ast

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

@en

type

label

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

@ast

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

@en

prefLabel

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

@ast

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

@en

P1433

Q35686885-45CDC082-7533-454B-9DDC-0C2059E526C0

P1476

Q35686885-0ACAB630-CDA1-46E9-9304-2B591382F49D

P2093

Q35686885-24DE640A-34CC-4396-9FAF-DB2D41D387B4

Q35686885-5C63FED9-460D-4D06-B690-0CF16B882EE6

Q35686885-68E164F7-BB99-4E3A-AFED-7D9ED1B6C170

Q35686885-B303FF25-400F-482A-9902-7DC2FDA01735

Q35686885-B30F1112-F1E4-47C9-B046-273EFE98A034

Q35686885-EAF5D674-125A-4C62-BDCF-2E3D896B4CF5

P2860

Q35686885-00A83EBA-B48B-4AFC-8CBD-B068E601BC87

Q35686885-03419962-74BF-44B9-832E-EE89D5C18A77

Q35686885-03806412-9F27-4319-9754-B81F625AAC48

Q35686885-0A8681E8-8382-40DD-8115-5CCA0E076779

Q35686885-0B3921A2-633E-4EC9-803D-103E88A18062

Q35686885-0F32A21A-3AB7-44E6-A4B4-823BB9F68BA1

Q35686885-14653EC9-AE4D-4F8F-BE27-A32A14800EAC

Q35686885-14B60DFA-3B99-4160-8589-D304269E9F84

Q35686885-163124AA-7D24-471B-A97E-CAEBA5A1D6A5

Q35686885-19012A9F-7836-4302-B769-79046E4C3CEF

P304

Q35686885-C997C395-EB2E-4F99-8183-F303F55584B4

P31

Q35686885-5EFC4128-4ED2-4880-AE43-82A1333E25D5

P356

Q35686885-66220AD3-D07F-40BF-8171-DB901ECBA416

P407

Q35686885-49ABA3C3-41DA-4CAE-B76F-7490FC75D4BE

P433

Q35686885-C4C49A8B-0875-4EC0-9FC6-891028539019

P478

Q35686885-7AE62FBD-CF41-4456-B25A-89079F4FE076

P50

Q35686885-78B693EC-DE39-4E1A-94AD-F0A7E13ECAE8

P577

Q35686885-0869876B-087E-42C9-B119-20DACCD36CC1

P5875

Q35686885-DDA0C47C-95F0-4788-AA65-768D2DE0A722

P698

Q35686885-FD3F32AB-ABC2-4BB3-8E0D-98899732AEEF

P932

Q35686885-2DA0A9B5-EAD5-4892-BAA1-D6ECF2C89827

P356

JIMMUNOL.1002176

P1433

Journal of Immunology

P1476

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

@en

P2093

Ali Torkamani

http://www.w3.org/2001/XMLSchema#string

Amanda L Gavin

http://www.w3.org/2001/XMLSchema#string

Bao H Duong

http://www.w3.org/2001/XMLSchema#string

Colleen M Doyle

http://www.w3.org/2001/XMLSchema#string

Miyo Ota

http://www.w3.org/2001/XMLSchema#string

Takayuki Ota

http://www.w3.org/2001/XMLSchema#string

P2860

DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF

Basic local alignment search tool

APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity

Peripheral B cell maturation. I. Immature peripheral B cells in adults are heat-stable antigenhi and exhibit unique signaling characteristics

Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells

BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses

BCMA is essential for the survival of long-lived bone marrow plasma cells

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

Prevention of murine antiphospholipid syndrome by BAFF blockade

P304

4128-4136

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.1002176

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

185

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-09-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

46149230

http://www.w3.org/2001/XMLSchema#string

P698

20817867

http://www.w3.org/2001/XMLSchema#string

P932

3263398

http://www.w3.org/2001/XMLSchema#string