Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. - Wikidata - wikimedia - TriplyDB

Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.

Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.

http://www.wikidata.org/entity/Q35688037

about

Expanding the ubiquitin code through post-translational modification The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications Mending a broken heart: the role of mitophagy in cardioprotection Autophagosome dynamics in neurodegeneration at a glance Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress.A PGAM5-KEAP1-Nrf2 complex is required for stress-induced mitochondrial retrograde trafficking.Mitochondrial autophagy in cardiomyopathy.6-OHDA-Induced Changes in Parkinson's Disease-Related Gene Expression are not Affected by the Overexpression of PGAM5 in In Vitro Differentiated Embryonic Mesencephalic Cells.Parkin and mitophagy in cancer.Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury.Expanding perspectives on the significance of mitophagy in cancer.Mitochondrial phosphatase PGAM5 regulates Keap1-mediated Bcl-xL degradation and controls cardiomyocyte apoptosis driven by myocardial ischemia/reperfusion injury.Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila.The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4(+) T Cells.Regulation of mitophagy by the ubiquitin pathway in neurodegenerative diseases.Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights.Mitochondrial morphology and cellular distribution are altered in SPG31 patients and are linked to DRP1 hyperphosphorylation.High PGAM5 expression induces chemoresistance by enhancing Bcl-xL-mediated anti-apoptotic signaling and predicts poor prognosis in hepatocellular carcinoma patients

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P2860

Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.

http://www.wikidata.org/entity/Q35688037

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

Genetic deficiency of the mito ...... nson's-like movement disorder.

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Genetic deficiency of the mito ...... nson's-like movement disorder.

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type

label

Genetic deficiency of the mito ...... nson's-like movement disorder.

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Genetic deficiency of the mito ...... nson's-like movement disorder.

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prefLabel

Genetic deficiency of the mito ...... nson's-like movement disorder.

@ast

Genetic deficiency of the mito ...... nson's-like movement disorder.

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P1433

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P1433

Nature Communications

P1476

Genetic deficiency of the mito ...... nson's-like movement disorder.

@en

P2093

Brittany Chao

http://www.w3.org/2001/XMLSchema#string

Danielle A Springer

http://www.w3.org/2001/XMLSchema#string

Lixin Zheng

http://www.w3.org/2001/XMLSchema#string

Michael Lenardo

http://www.w3.org/2001/XMLSchema#string

Michele D Allen

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Senthilkumar S Karuppagounder

http://www.w3.org/2001/XMLSchema#string

Valina L Dawson

http://www.w3.org/2001/XMLSchema#string

Wei Lu

http://www.w3.org/2001/XMLSchema#string

Yan Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder

Mitochondria and mitophagy: the yin and yang of cell death control

Mechanisms of mitophagy

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.

Induction of intestinal Th17 cells by segmented filamentous bacteria

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4930

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scholarly article

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10.1038/NCOMMS5930

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P478

5

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2014-09-15T00:00:00Z

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25222142

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Parkinson's disease

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4457367

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