Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder
about
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondriaParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1The benefits of humanized yeast models to study Parkinson's diseaseUse of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimersMorphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathwayMitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell NecroptosisSmall, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation.Aconitase causes iron toxicity in Drosophila pink1 mutantsGenetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice.Mitochondrial Ca(2+) and neurodegenerationCognitive Impairment Associated with Parkinson's Disease: Role of Mitochondria.Autophagy in axonal and dendritic degeneration.Critical role of calpain in spinal cord degeneration in Parkinson's diseaseThe synaptic function of LRRK2.Mitochondrial permeability transition pore: a promising target for the treatment of Parkinson's disease.Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.Intramembrane proteases as drug targets.Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome.Mitochondrial Mg(2+) homeostasis decides cellular energy metabolism and vulnerability to stress.SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy.Approaches for discovering novel bioactive small molecules targeting autophagy.
P2860
Q21563375-BECCF11A-4976-4D33-B6DB-E93B8C04DB31Q24308897-FA1A74A4-0BD8-4A55-BA6F-4690CB0E1237Q26853041-0B99E307-CBE9-4D33-AE3D-50FF91221A9BQ27683814-9538E42B-4878-46BE-8E5C-5983E7370220Q28396161-414FCB9E-7738-4AFE-A0AC-351490F488F3Q28552780-6B326D3A-1EF4-4B91-9979-C95DDAB7EA9DQ34230329-2BF39313-259D-4BC5-AF57-898CED627044Q34699834-A2DAE7D1-AF7C-45C3-A34A-E8CEEA76FD67Q35688037-59811F12-33E2-48EF-97F8-639A30F70FC7Q35859792-D9044240-C9E2-4037-95C5-C011F2329CE4Q36095330-5FF23A94-E6FF-4EA7-9659-C6D6BCDA9A14Q37168743-F7BA045B-B7A9-481D-9838-F7A8BD55D714Q37208557-8DD46FD6-F915-4B12-B8E1-10194CE1B09DQ37384896-58FEF188-2BB8-483F-A773-069957818431Q38044429-8AECA701-6F64-45A7-A401-2FD2DF698B2BQ38716156-29DC43D9-3626-469B-8518-EEA918C7167CQ38784992-A0AE2420-E2B6-462A-B9BB-1FC0FF395AFBQ38790377-E6A6C7F3-A340-4148-A786-4B445E89AB12Q41040861-5E0F3031-CABC-40DF-840F-6285C37DF36EQ41837078-2BAAC066-5D45-4377-9471-41ACFB6F2AEBQ47233712-F721EBD1-3308-4001-B449-4F7F31EDEB60Q48708365-47D5AC91-7792-4D94-B798-066703698ABD
P2860
Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mitochondrial dynamics and mit ...... l in a major movement disorder
@ast
Mitochondrial dynamics and mit ...... l in a major movement disorder
@en
Mitochondrial dynamics and mit ...... l in a major movement disorder
@nl
type
label
Mitochondrial dynamics and mit ...... l in a major movement disorder
@ast
Mitochondrial dynamics and mit ...... l in a major movement disorder
@en
Mitochondrial dynamics and mit ...... l in a major movement disorder
@nl
prefLabel
Mitochondrial dynamics and mit ...... l in a major movement disorder
@ast
Mitochondrial dynamics and mit ...... l in a major movement disorder
@en
Mitochondrial dynamics and mit ...... l in a major movement disorder
@nl
P2860
P3181
P1476
Mitochondrial dynamics and mit ...... l in a major movement disorder
@en
P2093
Bingwei Lu
Yuzuru Imai
P2860
P304
P3181
P356
10.1016/J.CONB.2011.10.016
P407
P577
2011-12-01T00:00:00Z