Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans
about
Collagen structure and stabilityProlyl 4-hydroxylaseGenetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegansStringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylaseLoss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null miceGenetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV-mediated basement membrane integrity during late elongation of the embryo2005 Emil Thomas Kaiser Award.4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helixConformational preferences of substrates for human prolyl 4-hydroxylaseCollagens and collagen-related diseases.Regulation of axonal midline guidance by prolyl 4-hydroxylation in Caenorhabditis elegans.Mutation of TweedleD, a member of an unconventional cuticle protein family, alters body shape in DrosophilaThe invertebrate Caenorhabditis elegans biosynthesizes ascorbate.Bioavailable affinity label for collagen prolyl 4-hydroxylase.Origin of the stability conferred upon collagen by fluorinationHuman Collagen Prolyl 4-Hydroxylase Is Activated by Ligands for Its Iron Center.Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond.COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets.Prolyl 4 hydroxylase: a critical target in the pathophysiology of diseases.A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase.The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.4-Fluoroprolines: Conformational Analysis and Effects on the Stability and Folding of Peptides and Proteins.Stronger and (now) longer synthetic collagen.Cloning and characterization of a low molecular weight prolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylation of proline-rich, collagen-like, and hypoxia-inducible transcription factor alpha-like peptides.Direct and continuous assay for prolyl 4-hydroxylase.Egg shell collagen formation in Caenorhabditis elegans involves a novel prolyl 4-hydroxylase expressed in spermatheca and embryos and possessing many unique properties.Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes.Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in Km values for peptide substrates with increasing chain length: mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half.Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct.The Caenorhabditis elegans ERp60 homolog protein disulfide isomerase-3 has disulfide isomerase and transglutaminase-like cross-linking activity and is involved in the maintenance of body morphology.Chlamydomonas reinhardtii has multiple prolyl 4-hydroxylases, one of which is essential for proper cell wall assembly.
P2860
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P2860
Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
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name
Prolyl 4-hydroxylase is requir ...... esis in Caenorhabditis elegans
@ast
Prolyl 4-hydroxylase is requir ...... esis in Caenorhabditis elegans
@en
type
label
Prolyl 4-hydroxylase is requir ...... esis in Caenorhabditis elegans
@ast
Prolyl 4-hydroxylase is requir ...... esis in Caenorhabditis elegans
@en
prefLabel
Prolyl 4-hydroxylase is requir ...... esis in Caenorhabditis elegans
@ast
Prolyl 4-hydroxylase is requir ...... esis in Caenorhabditis elegans
@en
P2093
P2860
P356
P1476
Prolyl 4-hydroxylase is requir ...... esis in Caenorhabditis elegans
@en
P2093
P2860
P304
P356
10.1073/PNAS.97.9.4736
P407
P577
2000-04-01T00:00:00Z