Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes.
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Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variantAdipocyte extracellular matrix composition, dynamics and role in obesityThe Role of Oxygen Sensors, Hydroxylases, and HIF in Cardiac Function and DiseaseHypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1)Activation of the prolyl-hydroxylase oxygen-sensing signal cascade leads to AMPK activation in cardiomyocytesSuppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development.Myocardial hypoxia-inducible HIF-1alpha, VEGF, and GLUT1 gene expression is associated with microvascular and ICAM-1 heterogeneity during endotoxemia.Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells.Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS.Environmental oxygen tension regulates the energy metabolism and self-renewal of human embryonic stem cellsHypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cellsOxidative stress and oxidant signaling in obstructive sleep apnea and associated cardiovascular diseases.Endocytic function of von Hippel-Lindau tumor suppressor protein regulates surface localization of fibroblast growth factor receptor 1 and cell motilityO(2)-sensing signal cascade: clamping of O(2) respiration, reduced ATP utilization, and inducible fumarate respiration.Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes.Activation of the oxygen-sensing signal cascade prevents mitochondrial injury after mouse liver ischemia-reperfusion.Bioavailable affinity label for collagen prolyl 4-hydroxylase.HIF-1α in heart: protective mechanisms.Prolyl 4 hydroxylase: a critical target in the pathophysiology of diseases.Ethyl 3,4-dihydroxy benzoate, a unique preconditioning agent for alleviating hypoxia-mediated oxidative damage in L6 myoblasts cells.Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C?Analysis of the hypoxia-sensing pathway in Drosophila melanogaster.Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetiExpression and actions of HIF prolyl-4-hydroxylase in the rat kidneys.Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells.
P2860
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P2860
Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Activation of the prolyl hydro ...... inhibition to cardiomyocytes.
@en
Activation of the prolyl hydro ...... inhibition to cardiomyocytes.
@nl
type
label
Activation of the prolyl hydro ...... inhibition to cardiomyocytes.
@en
Activation of the prolyl hydro ...... inhibition to cardiomyocytes.
@nl
prefLabel
Activation of the prolyl hydro ...... inhibition to cardiomyocytes.
@en
Activation of the prolyl hydro ...... inhibition to cardiomyocytes.
@nl
P2093
P2860
P356
P1476
Activation of the prolyl hydro ...... inhibition to cardiomyocytes.
@en
P2093
Charles Steenbergen
Elizabeth Murphy
Gary Wright
Joshua J Higgin
P2860
P304
20235-20239
P356
10.1074/JBC.M301391200
P407
P577
2003-03-20T00:00:00Z