A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

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A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

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A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

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A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

@ast

A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

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prefLabel

A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

@ast

A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

@en

P1476

A five-membered lactone prodrug of CBI-based analogs of the duocarmycins

@en

P2093

Dale L Boger

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Daniel M Brody

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Mika Uematsu

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P2860

CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents

A strategy for tumor-selective chemotherapy by enzymatic liberation of seco-duocarmycin SA-derivatives from nontoxic prodrugs

A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding.

Duocarmycin A, a new antitumor antibiotic from Streptomyces.

Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation

Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.

Asymmetric synthesis of a CBI-based cyclic N-acyl O-amino phenol duocarmycin prodrug.

Duocarmycins--natures prodrugs?

Mechanisms of in situ activation for DNA-targeting antitumor agents.

Asymmetric synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI).

P304

3101-3104

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P31

scholarly article

P356

10.1016/J.TETLET.2014.11.038

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2015-06-01T00:00:00Z

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P698

26069351

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P932

4459655

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