RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice. - Wikidata - wikimedia - TriplyDB

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

http://www.wikidata.org/entity/Q35698873

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Development of the mammalian lymphatic vasculature Evidence for SH2 domain-containing 5'-inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunction Genetics of lymphatic anomalies Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man.Emerging lymphatic imaging technologies for mouse and man.An abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in Dercum's disease.In vivo lymphatic imaging of a human inflammatory breast cancer model.RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity.Loss of NF1 expression in human endothelial cells promotes autonomous proliferation and altered vascular morphogenesis.Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function Ras/MAPK signaling modulates VEGFR-3 expression through Ets-mediated p300 recruitment and histone acetylation on the Vegfr3 gene in lymphatic endothelial cells.Blood vascular abnormalities in Rasa1(R780Q) knockin mice: implications for the pathogenesis of capillary malformation-arteriovenous malformation.C/EBP-β-activated microRNA-223 promotes tumour growth through targeting RASA1 in human colorectal cancer.Pediatric lymphatic malformations: evolving understanding and therapeutic options.Altered lymphatic function and architecture in salt-induced hypertension assessed by near-infrared fluorescence imaging Molecular regulation of lymphangiogenesis in development and tumor microenvironment.Regulation of Ras signal transduction during T cell development and activation.Endothelial ERK signaling controls lymphatic fate specification Direct visualization of changes of lymphatic function and drainage pathways in lymph node metastasis of B16F10 melanoma using near-infrared fluorescence imaging.Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation Characterization of internodal collecting lymphatic vessel function after surgical removal of an axillary lymph node in mice Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.Nonredundant functions for Ras GTPase-activating proteins in tissue homeostasis.Capillary malformation--arteriovenous malformation syndrome: review of the literature, proposed diagnostic criteria, and recommendations for management.Lymphatic vessel abnormalities arising from disorders of Ras signal transduction.RASA1 regulates the function of lymphatic vessel valves in mice.Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function Lymphatic pumping: mechanics, mechanisms and malfunction.Modeling RASopathies with Genetically Modified Mouse Models.Vascular heterogeneity and specialization in development and disease.Intestinal lymphatic vasculature: structure, mechanisms and functions.Non-invasive optical imaging of the lymphatic vasculature of a mouse.CM-AVM syndrome in a neonate: case report and treatment with a novel flow reduction strategy.Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors.Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations.Experimental Models Used to Assess Lymphatic Contractile Function.Somatic second hit mutation of RASA1 in vascular endothelial cells in capillary malformation-arteriovenous malformation.

P2860

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P2860

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

http://www.wikidata.org/entity/Q35698873

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

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RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

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type

label

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

@ast

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

@en

prefLabel

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

@ast

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

@en

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P1433

Journal of Clinical Investigation

P1476

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice.

@en

P2093

Beth A Lubeck

http://www.w3.org/2001/XMLSchema#string

Eva Sevick-Muraca

http://www.w3.org/2001/XMLSchema#string

John E Wilkinson

http://www.w3.org/2001/XMLSchema#string

Philip D King

http://www.w3.org/2001/XMLSchema#string

Philip E Lapinski

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R Sathish Srinivasan

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Sunkuk Kwon

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P2860

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation

Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations

MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

Functionally specialized junctions between endothelial cells of lymphatic vessels

Role of p120 Ras-GAP in directed cell movement

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Mammalian MAP kinase signalling cascades

RASA1: variable phenotype with capillary and arteriovenous malformations

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

GEFs and GAPs: critical elements in the control of small G proteins

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733-747

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10.1172/JCI46116

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2

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122

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22232212

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3266774

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