Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease.

Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease.

http://www.wikidata.org/entity/Q35699583

about

Chaperones of F1-ATPase Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress.What we can learn from animal models about cerebral multi-morbidity.Icariin reduces α-synuclein over-expression by promoting α-synuclein degradation.Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons α-Synuclein increases β-amyloid secretion by promoting β-/γ-secretase processing of APP.Why the maternal brain?Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses.Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates.Characteristics of human lysozyme and its disease-related mutants in their unfolded states.The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease-related pathology.Inhibition of amyloid-β plaque formation by α-synuclein.

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P2860

Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease.

http://www.wikidata.org/entity/Q35699583

description

2007 nî lūn-bûn

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Lack of alpha-synuclein increa ...... model of Alzheimer's disease.

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Erica Peethumnongsin

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Hui Zheng

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Verena Kallhoff

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P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

The gamma-secretase complex: membrane-embedded proteolytic ensemble

Neuronal accumulation of alpha- and beta-synucleins in the brain of a GM2 gangliosidosis mouse model

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

Genetic mouse models of parkinsonism: strengths and limitations.

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.

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10.1186/1750-1326-2-6

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Alzheimer's disease

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