Human cytomegalovirus-encoded G protein-coupled receptor US28 mediates smooth muscle cell migration through Galpha12.
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Consensus on the role of human cytomegalovirus in glioblastomaDifferential ligand binding to a human cytomegalovirus chemokine receptor determines cell type-specific motility.Cytomegalovirus Restructures Lipid Rafts via a US28/CDC42-Mediated Pathway, Enhancing Cholesterol Efflux from Host Cells.Molecular mechanisms deployed by virally encoded G protein-coupled receptors in human diseases.A method for quantifying mechanical properties of tissue following viral infectionCytomegalovirus microRNA expression is tissue specific and is associated with persistenceConstitutive β-catenin signaling by the viral chemokine receptor US28US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cellsHCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinaseModulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Rat cytomegalovirus gene expression in cardiac allograft recipients is tissue specific and does not parallel the profiles detected in vitroGα13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.Signaling and regulation of G-protein coupled receptors encoded by cytomegaloviruses.Cytomegalovirus CC chemokine promotes immune cell migration.Acceleration of allograft failure by cytomegalovirusDesensitization of herpesvirus-encoded G protein-coupled receptors.Functional analysis of human cytomegalovirus pUS28 mutants in infected cells.The chemokine receptor homologue encoded by US27 of human cytomegalovirus is heavily glycosylated and is present in infected human foreskin fibroblasts and enveloped virus particles.The carboxy-terminal tail of human cytomegalovirus (HCMV) US28 regulates both chemokine-independent and chemokine-dependent signaling in HCMV-infected cells.International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors.Human Cytomegalovirus US28: a functionally selective chemokine binding receptor.US28, a Virally-Encoded GPCR as an Antiviral Target for Human Cytomegalovirus Infection.Therapeutic potential of CCR1 antagonists for multiple myeloma.Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?The HCMV US28 vGPCR induces potent Gαq/PLC-β signaling in monocytes leading to increased adhesion to endothelial cells.Hijacking GPCRs by viral pathogens and tumor.Receptor chimeras demonstrate that the C-terminal domain of the human cytomegalovirus US27 gene product is necessary and sufficient for intracellular receptor localization.Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28.Mouse cytomegalovirus M33 is necessary and sufficient in virus-induced vascular smooth muscle cell migration.Migrating anterior mesoderm cells and intercalating trunk mesoderm cells have distinct responses to Rho and Rac during Xenopus gastrulation.US28: HCMV's Swiss Army KnifeThe Human Cytomegalovirus, from Oncomodulation to Oncogenesis
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P2860
Human cytomegalovirus-encoded G protein-coupled receptor US28 mediates smooth muscle cell migration through Galpha12.
description
2004 nî lūn-bûn
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name
Human cytomegalovirus-encoded ...... ll migration through Galpha12.
@ast
Human cytomegalovirus-encoded ...... ll migration through Galpha12.
@en
type
label
Human cytomegalovirus-encoded ...... ll migration through Galpha12.
@ast
Human cytomegalovirus-encoded ...... ll migration through Galpha12.
@en
prefLabel
Human cytomegalovirus-encoded ...... ll migration through Galpha12.
@ast
Human cytomegalovirus-encoded ...... ll migration through Galpha12.
@en
P2093
P2860
P1433
P1476
Human cytomegalovirus-encoded ...... ll migration through Galpha12.
@en
P2093
Alec J Hirsch
Daniel N Streblow
Dora Pancheva
Jay A Nelson
Patricia P Smith
Ryan M Melnychuk
P2860
P304
P356
10.1128/JVI.78.15.8382-8391.2004
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P577
2004-08-01T00:00:00Z