Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4 - Wikidata - wikimedia - TriplyDB

Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

http://www.wikidata.org/entity/Q35705851

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Cytokine effects on the basal ganglia and dopamine function: the subcortical source of inflammatory malaise Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative Functions in Rats Hypothalamic TLR2 triggers sickness behavior via a microglia-neuronal axis Mechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cells Gene expression in brain and liver produced by three different regimens of alcohol consumption in mice: comparison with immune activation Inflamed In Vitro Retina: Cytotoxic Neuroinflammation and Galectin-3 Expression Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro Central Nervous System: (Immunological) Ivory Tower or Not?LRP1 expression in microglia is protective during CNS autoimmunity.Early-life enteric infections: relation between chronic systemic inflammation and poor cognition in children Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain.Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation.LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface.A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation Chronic caffeine ingestion causes microglia activation, but not proliferation in the healthy brain BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals p21Cip restrains hippocampal neurogenesis and protects neuronal progenitors from apoptosis during acute systemic inflammation.The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.Cuprizone does not induce CNS demyelination in nonhuman primates.Altered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints Chronic intestinal inflammation alters hippocampal neurogenesis.Cognitive impairment in multiple sclerosis: clinical, radiologic and pathologic insights.Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis.Microglia: scapegoat, saboteur, or something else?Systemic inflammation and microglial activation: systematic review of animal experiments Preclinical evaluation of SMM-189, a cannabinoid receptor 2-specific inverse agonist.Blood-Brain Barrier Deterioration and Hippocampal Gene Expression in Polymicrobial Sepsis: An Evaluation of Endothelial MyD88 and the Vagus Nerve Cecal Ligation and Puncture Results in Long-Term Central Nervous System Myeloid Inflammation.Repetitive acute intermittent hypoxia does not promote generalized inflammatory gene expression in the rat CNS.Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins.Developmental time course and effects of immunostressors that alter hormone-responsive behavior on microglia in the peripubertal and adult female mouse brain.Sequential activation of microglia and astrocyte cytokine expression precedes increased Iba-1 or GFAP immunoreactivity following systemic immune challenge.Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury New tools for studying microglia in the mouse and human CNS.LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland.Endotoxemia-induced cytokine-mediated responses of hippocampal astrocytes transmitted by cells of the brain-immune interface.Activated microglia enhance neurogenesis via trypsinogen secretion.Microglia and ischemic stroke: a double-edged sword.

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Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

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Lipopolysaccharide-induced mic ...... dependent of hematogenous TLR4

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JNEUROSCI.0730-12.2012

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Journal of Neuroscience

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Lipopolysaccharide-induced mic ...... dependent of hematogenous TLR4

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Bruce D Trapp

http://www.w3.org/2001/XMLSchema#string

Cornelia C Bergmann

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Grahame J Kidd

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Karl B Shpargel

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Kenneth T Farabaugh

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Ranjan Dutta

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Stephen A Stohlman

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Walid Jalabi

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Xinghua Yin

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Zhihong Chen

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P2860

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4

Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and nuclear factor kappa B activity in the brain during endotoxemia

Synaptic pruning by microglia is necessary for normal brain development

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

Microglial physiology: unique stimuli, specialized responses

Hypothermia-induced ischemic tolerance.

The development of neural stem cells.

Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. An immunohistochemical study using a novel monoclonal antibody.

Microglia as neuroprotective, immunocompetent cells of the CNS.

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11706-11715

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scholarly article

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10.1523/JNEUROSCI.0730-12.2012

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34

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32

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2012-08-01T00:00:00Z

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22915113

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Toll-like receptor

lipopolysaccharide

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4461442

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