NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase
about
Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cellsThe dual effect of the particulate and organic components of diesel exhaust particles on the alteration of pulmonary immune/inflammatory responses and metabolic enzymesInhalation exposure of rats to asphalt fumes generated at paving temperatures alters pulmonary xenobiotic metabolism pathways without lung injuryCorrelation between CYP1A1 transcript, protein level, enzyme activity and DNA adduct formation in normal human mammary epithelial cell strains exposed to benzo[a]pyreneDisruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancerCancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient airSodium arsenite-induced stress-related gene expression in normal human epidermal, HaCaT, and HEL30 keratinocytes.Idebenone and neuroprotection: antioxidant, pro-oxidant, or electron carrier?Hydroquinones cause specific mutations and lead to cellular transformation and in vivo tumorigenesisPulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrenePesticides, gene polymorphisms, and bladder cancer among Egyptian agricultural workersNrf2-dependent induction of NQO1 in mouse aortic endothelial cells overexpressing catalaseNrf2 signaling and cell survivalEmerging role of Nrf2 in adipocytes and adipose biologyNrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 geneDifferential gene expression in human conducting airway surface epithelia and submucosal glands.Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative StressImpact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons.Lack of association between NADPH quinone oxidoreductase 1 (NQO1) gene C609T polymorphism and lung cancer: a case-control study and a meta-analysisBioactivation of polycyclic aromatic hydrocarbon carcinogens within the vascular wall: implications for human atherogenesis.NQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation.Genetic susceptibility to tobacco-related cancer.Quinone reductases multitasking in the metabolic world.NQO1, MPO, and the risk of lung cancer: a HuGE review.NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones.Simultaneous determination of benzo[a]pyrene and eight of its metabolites in Fundulus heteroclitus bile using ultra-performance liquid chromatography with mass spectrometryBladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.Enhancement of radiation effect using beta-lapachone and underlying mechanism.5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder.Association of the GSTP1 and NQO1 polymorphisms and head and neck squamous cell carcinoma risk.Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli.Genetic polymorphisms in NQO1 and SOD2: interactions with smoking, schistosoma infection, and bladder cancer risk in Egypt.System review and metaanalysis of the relationships between five metabolic gene polymorphisms and colorectal adenoma risk.Genotoxicity of complex PAH mixtures recovered from contaminated lake sediments as assessed by three different methods.Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry.Detection of quinone oxidoreductase 1 (NQO1) single-nucleotide polymorphisms (SNP) related to benzene metabolism in immortalized B lymphocytes from a Chinese Han population.Heat shock increases expression of NAD(P)H:quinone oxidoreductase (NQO1), mediator of beta-lapachone cytotoxicity, by increasing NQO1 gene activity and via Hsp70-mediated stabilisation of NQO1 protein.Genetic polymorphisms in glutathione S-transferase T1 affect the surgical outcome of varicocelectomies in infertile patients.Biological interaction of cigarette smoking on the association between genetic polymorphisms involved in inflammation and the risk of lung cancer: A case-control study in Japan.
P2860
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P2860
NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
NAD(P)H:quinone oxidoreductase ...... ome P4501A1 and P450 reductase
@ast
NAD(P)H:quinone oxidoreductase ...... ome P4501A1 and P450 reductase
@en
type
label
NAD(P)H:quinone oxidoreductase ...... ome P4501A1 and P450 reductase
@ast
NAD(P)H:quinone oxidoreductase ...... ome P4501A1 and P450 reductase
@en
prefLabel
NAD(P)H:quinone oxidoreductase ...... ome P4501A1 and P450 reductase
@ast
NAD(P)H:quinone oxidoreductase ...... ome P4501A1 and P450 reductase
@en
P2860
P356
P1476
NAD(P)H:quinone oxidoreductase ...... ome P4501A1 and P450 reductase
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.18.8413
P407
P577
1994-08-01T00:00:00Z