Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA.
about
Pseudocomplementary PNAs as selective modifiers of protein activity on duplex DNA: the case of type IIs restriction enzymesDeveloping a programmed restriction endonuclease for highly specific DNA cleavageEnd invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes.Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription startCrystal Structure of Chiral γPNA with Complementary DNA Strand: Insights into the Stability and Specificity of Recognition and Conformational PreorganizationSynthesis and monitored selection of nucleotide surrogates for binding T:A base pairs in homopurine-homopyrimidine DNA triple helices.Chemical approaches to control gene expression.Oligonucleotides and derivatives as gene-specific control agents.Targeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acidsAccelerated photobleaching of a cyanine dye in the presence of a ternary target DNA, PNA probe, dye catalytic complex: a molecular diagnosticNanopore based sequence specific detection of duplex DNA for genomic profiling.Strand invasion by mixed base PNAs and a PNA-peptide chimeraInvader LNA: efficient targeting of short double stranded DNA.Peptide nucleic acid (PNA) binding-mediated gene regulation.Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids.Peptide nucleic acids as antibacterial agents via the antisense principle.Cooperative hybridization of γPNA miniprobes to a repeating sequence motif and application to telomere analysis.Specific versus nonspecific binding of cationic PNAs to duplex DNARecognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O2'-alkylated RNA monomers.Inducing and modulating anisotropic DNA bends by pseudocomplementary peptide nucleic acids.Selection of RNA aptamers that bind HIV-1 LTR DNA duplexes: strand invaders.Clear-cut observation of PNA invasion using nanomechanical DNA origami devices.Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions.Sequence specificity at targeting double-stranded DNA with a γ-PNA oligomer modified with guanidinium G-clamp nucleobases.Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition.Orientation preferences of backbone secondary amide functional groups in peptide nucleic acid complexes: quantum chemical calculations reveal an intrinsic preference of cationic D-amino acid-based chiral PNA analogues for the P-form.Recent advances in the development of peptide nucleic acid as a gene-targeted drug.Chemical modification of Ce(IV)/EDTA-based artificial restriction DNA cutter for versatile manipulation of double-stranded DNA.Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications.Synthesis and characterization of oligodeoxyribonucleotides modified with 2'-thio-2'-deoxy-2'-S-(pyren-1-yl)methyluridineBulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles.Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes.Fluorescent intercalator displacement replacement (FIDR) assay: determination of relative thermodynamic and kinetic parameters in triplex formation--a case study using triplex-forming LNAsMerging Two Strategies for Mixed-Sequence Recognition of Double-Stranded DNA: Pseudocomplementary Invader Probes.New peptide nucleic acid analogues: synthesis and applications.RecA-mediated strand invasion of DNA by oligonucleotides substituted with 2-aminoadenine and 2-thiothymine.Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA.Invaders: Recognition of Double-Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2'-O-(Pyren-1-yl)methyl-ribonucleotidesStrand invasion of extended, mixed-sequence B-DNA by gammaPNAs.Recognition of mixed-sequence DNA duplexes: design guidelines for invaders based on 2'-O-(pyren-1-yl)methyl-RNA monomers.
P2860
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P2860
Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Double duplex invasion by pept ...... geting of double-stranded DNA.
@ast
Double duplex invasion by pept ...... geting of double-stranded DNA.
@en
type
label
Double duplex invasion by pept ...... geting of double-stranded DNA.
@ast
Double duplex invasion by pept ...... geting of double-stranded DNA.
@en
prefLabel
Double duplex invasion by pept ...... geting of double-stranded DNA.
@ast
Double duplex invasion by pept ...... geting of double-stranded DNA.
@en
P2093
P2860
P356
P1476
Double duplex invasion by pept ...... geting of double-stranded DNA.
@en
P2093
P2860
P304
11804-11808
P356
10.1073/PNAS.96.21.11804
P407
P577
1999-10-01T00:00:00Z