Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up
about
Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer.Physiology and pathophysiology of the blood-brain barrier: P-glycoprotein and occludin trafficking as therapeutic targets to optimize central nervous system drug deliveryThe pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapyIn silico prediction of inhibition of promiscuous breast cancer resistance protein (BCRP/ABCG2)Role of Human Breast Cancer Related Protein versus P-Glycoprotein as an Efflux Transporter for Benzylpenicillin: Potential Importance at the Blood-Brain BarrierStrategies to improve delivery of anticancer drugs across the blood-brain barrier to treat glioblastoma.Therapeutic strategies to improve drug delivery across the blood-brain barrier.Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriersDrug-Resistant Epilepsy: Multiple Hypotheses, Few AnswersFactors influencing the CNS distribution of a novel MEK-1/2 inhibitor: implications for combination therapy for melanoma brain metastasesThe cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells.Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brainAntitumor activity of (R,R')-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mouseEffect of prostaglandin E2 on multidrug resistance transporters in human placental cells.Gold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications.Inhibiting drug efflux transporters improves efficacy of ALS therapeuticsABC transporter-driven pharmacoresistance in Amyotrophic Lateral Sclerosis.Regulation of ABC transporters at the blood-brain barrier.Candidate drug targets for prevention or modification of epilepsyQuantitative proteomics of transporter expression in brain capillary endothelial cells isolated from P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and P-gp/Bcrp knockout miceCNS Anticancer Drug Discovery and Development Conference White Paper.Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma.Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma.Efflux transporters at the blood-brain barrier limit delivery and efficacy of cyclin-dependent kinase 4/6 inhibitor palbociclib (PD-0332991) in an orthotopic brain tumor modelRegulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders.A novel PET protocol for visualization of breast cancer resistance protein function at the blood-brain barrier.Function of the blood-brain barrier and restriction of drug delivery to invasive glioma cells: findings in an orthotopic rat xenograft model of glioma.Factors Influencing the Central Nervous System Distribution of a Novel Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GSK2126458: Implications for Overcoming Resistance with Combination Therapy for Melanoma Brain Metastases.Association between ABCB1 Polymorphisms and Ischemic Stroke in Korean PopulationThe dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord.The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokinesPharmacokinetics of single ascending doses of the P-glycoprotein inhibitor tariquidar in healthy subjects.Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomographyBreast cancer resistance protein (Bcrp) and the testis--an unexpected turn of events.Pilot PET Study to Assess the Functional Interplay Between ABCB1 and ABCG2 at the Human Blood-Brain BarrierP-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer modelPharmacokinetic assessment of efflux transport in sunitinib distribution to the brain.Bioluminescent imaging of drug efflux at the blood-brain barrier mediated by the transporter ABCG2Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis.
P2860
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P2860
Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Breast cancer resistance prote ...... ancer: two gatekeepers team up
@ast
Breast cancer resistance prote ...... ancer: two gatekeepers team up
@en
type
label
Breast cancer resistance prote ...... ancer: two gatekeepers team up
@ast
Breast cancer resistance prote ...... ancer: two gatekeepers team up
@en
prefLabel
Breast cancer resistance prote ...... ancer: two gatekeepers team up
@ast
Breast cancer resistance prote ...... ancer: two gatekeepers team up
@en
P2093
P2860
P1476
Breast cancer resistance prote ...... ancer: two gatekeepers team up
@en
P2093
Anika M S Hartz
Björn Bauer
Sagar Agarwal
William F Elmquist
P2860
P304
P356
10.2174/138161211797440186
P577
2011-01-01T00:00:00Z