Abcg2/Bcrp1 mediates the polarized transport of antiretroviral nucleosides abacavir and zidovudine
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Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug deliveryDeterminants of the activity and substrate recognition of breast cancer resistance protein (ABCG2).N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin tXenobiotic, bile acid, and cholesterol transporters: function and regulation.Zidovudine and Lamivudine for HIV Infection.Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team upStereoselective interaction of pantoprazole with ABCG2. II. In vitro flux analysis.Few Drugs Display Flip-Flop Pharmacokinetics and These Are Primarily Associated with Classes 3 and 4 of the BDDCSBCRP/ABCG2 in the placenta: expression, function and regulation.Substrate-dependent breast cancer resistance protein (Bcrp1/Abcg2)-mediated interactions: consideration of multiple binding sites in in vitro assay design.The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research.Investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) on pharmacokinetics and central nervous system penetration of abacavir and zidovudine in the mouse.Interactions of tenofovir, Lamivudine, abacavir and Didanosine in primary human cells.Drug transporter pharmacogenetics in nucleoside-based therapies.Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.Pharmacokinetic and pharmacodynamic drug interactions between antiretrovirals and oral contraceptives.Differential gene expression in human hepatocyte cell lines exposed to the antiretroviral agent zidovudine.Xenobiotic transporters and kidney injury.Renal Drug Transporters and Drug Interactions.The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein.Multifunctional peptide-PEG intercalating conjugates: programmatic of gene delivery to the blood-brain barrier.Acute liver failure enhances oral plasma exposure of zidovudine in rats by downregulation of hepatic UGT2B7 and intestinal P-gp.Prediction of Drug Transfer into Milk Considering Breast Cancer Resistance Protein (BCRP)-Mediated Transport.The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes.Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population.Abacavir transmembrane transportabacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphateRole of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine.Drug Transport at the Brain and Endothelial Dysfunction in Preeclampsia: Implications and Perspectives
P2860
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P2860
Abcg2/Bcrp1 mediates the polarized transport of antiretroviral nucleosides abacavir and zidovudine
description
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juli 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/07/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/07/01)
@nl
наукова стаття, опублікована в липні 2007
@uk
مقالة علمية (نشرت في يوليو 2007)
@ar
name
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@ast
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@en
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@nl
type
label
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@ast
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@en
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@nl
prefLabel
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@ast
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@en
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@nl
P2093
P356
P1476
Abcg2/Bcrp1 mediates the polar ...... osides abacavir and zidovudine
@en
P2093
Nagdeep Giri
William F. Elmquist
P304
P356
10.1124/DMD.106.014274
P577
2007-07-01T00:00:00Z