Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.
about
Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesisVitamin D and Alzheimer's Disease: Neurocognition to TherapeuticsRemoving obstacles in neuroscience drug discovery: the future path for animal models.Epidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss.An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generationChanges in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau.Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tauAmyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice.Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic lossTranssynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network.Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease.Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's diseaseProtein aggregation containing β-amyloid, α-synuclein and hyperphosphorylated τ in cultured cells of hippocampus, substantia nigra and locus coeruleus after rotenone exposure.Ascidians: an invertebrate chordate model to study Alzheimer's disease pathogenesis.Neuroproteomics as a promising tool in Parkinson's disease research.Genetic ablation of luteinizing hormone receptor improves the amyloid pathology in a mouse model of Alzheimer diseaseConvergence of amyloid-beta and tau pathologies on mitochondria in vivo.Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons.Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis.Determination of odor detection threshold in the Gottingen minipig.Molecular brain imaging in the multimodality era.Tau gene transfer, but not alpha-synuclein, induces both progressive dopamine neuron degeneration and rotational behavior in the rat.Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease.Systematic analysis of gene expression in human brains before and after deathNeurological and psychiatric disorders as a neuroglial failure.The amyloid beta ion channel hypothesis of Alzheimer's disease.E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairmentThe small chaperone protein p23 and its cleaved product p19 in cellular stress.ENU mutagenesis screen to establish motor phenotypes in wild-type mice and modifiers of a pre-existing motor phenotype in tau mutant mice.Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease.Age and gender-dependent alternative splicing of P/Q-type calcium channel EF-hand.The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism.Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APPSw,Ind) mice.Aging of the brain, neurotrophin signaling, and Alzheimer's disease: is IGF1-R the common culprit?Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.Role of Lipids in Brain Injury and Diseases.An update on the toxicity of Abeta in Alzheimer's disease.Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep.Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.Lost in translation: neuropsychiatric drug development.
P2860
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P2860
Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Transgenic animal models of Al ...... thology, behavior and therapy.
@ast
Transgenic animal models of Al ...... thology, behavior and therapy.
@en
type
label
Transgenic animal models of Al ...... thology, behavior and therapy.
@ast
Transgenic animal models of Al ...... thology, behavior and therapy.
@en
prefLabel
Transgenic animal models of Al ...... thology, behavior and therapy.
@ast
Transgenic animal models of Al ...... thology, behavior and therapy.
@en
P2093
P356
P1433
P1476
Transgenic animal models of Al ...... athology, behavior and therapy
@en
P2093
Hoerndli F
Kurosinski P
Pennanen L
Streffer JR
P2888
P304
P356
10.1038/SJ.MP.4001508
P407
P50
P577
2004-07-01T00:00:00Z