Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair.
about
Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitorA Fluorescent Probe to Measure DNA Damage and RepairIDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer CellsUracil-DNA glycosylase expression determines human lung cancer cell sensitivity to pemetrexed.Expanding targets of DNAzyme-based sensors through deactivation and activation of DNAzymes by single uracil removal: sensitive fluorescent assay of uracil-DNA glycosylaseMetabolic effects of TiO2 nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytesInhibiting the DNA damage response as a therapeutic manoeuvre in cancer.Uracil DNA glycosylase (UNG) loss enhances DNA double strand break formation in human cancer cells exposed to pemetrexedInhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage.Standing the test of time: targeting thymidylate biosynthesis in cancer therapy.Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival.Structure-based virtual screening toward the discovery of novel inhibitors of the DNA repair activity of the human apurinic/apyrimidinic endonuclease 1.Dietary Methyl Donor Depletion Suppresses Intestinal Adenoma Development.Crystal structure of mimivirus uracil-DNA glycosylase.The cytotoxic effect of β-elemene against malignant glioma is enhanced by base-excision repair inhibitor methoxyamine.Phase I clinical trial of the base excision repair inhibitor methoxyamine in combination with fludarabine for patients with advanced hematologic malignancies.
P2860
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P2860
Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Removal of uracil by uracil DN ...... inhibit base excision repair.
@ast
Removal of uracil by uracil DN ...... inhibit base excision repair.
@en
type
label
Removal of uracil by uracil DN ...... inhibit base excision repair.
@ast
Removal of uracil by uracil DN ...... inhibit base excision repair.
@en
prefLabel
Removal of uracil by uracil DN ...... inhibit base excision repair.
@ast
Removal of uracil by uracil DN ...... inhibit base excision repair.
@en
P2093
P2860
P921
P356
P1476
Removal of uracil by uracil DN ...... inhibit base excision repair.
@en
P2093
A D Bulgar
N Oleinick
S L Gerson
S Markowitz
P2860
P2888
P356
10.1038/CDDIS.2011.135
P577
2012-01-12T00:00:00Z
P5875
P6179
1029727737