Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C
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Increased response to morphine in mice lacking protein kinase C epsilonSignal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channelIdentification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinaseMass spectrometric analysis reveals a functionally important PKA phosphorylation site in a Kir3 channel subunitTyrosine phosphorylation of Kir3 following kappa-opioid receptor activation of p38 MAPK causes heterologous desensitizationReceptor-induced depletion of phosphatidylinositol 4,5-bisphosphate inhibits inwardly rectifying K+ channels in a receptor-specific mannerA genetically encoded tool kit for manipulating and monitoring membrane phosphatidylinositol 4,5-bisphosphate in intact cells.Electrophysiological studies in Xenopus oocytes for the opening of Escherichia coli SecA-dependent protein-conducting channels.Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Galphaq-coupled receptorsEmerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.A Critical Gating Switch at a Modulatory Site in Neuronal Kir3 ChannelsDiverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding.The N-terminal domain of Slack determines the formation and trafficking of Slick/Slack heteromeric sodium-activated potassium channels.Calcium Release from Stores Inhibits GIRKThe ICl,swell inhibitor DCPIB blocks Kir channels that possess weak affinity for PIP2.Firing modes of dopamine neurons drive bidirectional GIRK channel plasticity.K(+) channels: function-structural overview.Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia.Activation of protein kinase C augments T-type Ca2+ channel activity without changing channel surface density.PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells.Protein kinase C dependent inhibition of the heteromeric Kir4.1-Kir5.1 channelMolecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase.Reduced 5-HT1A- and GABAB receptor function in dorsal raphé neurons upon chronic fluoxetine treatment of socially stressed rats.Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes.Substance P inhibits GABAB receptor signalling in the ventral tegmental area.Desensitization and tolerance of mu opioid receptors on pontine Kolliker-Fuse neurons.Hemispheric differences in the number of parvalbumin-positive neurons in subdivisions of the rat basolateral amygdala complex.Decrease in PIP(2) channel interactions is the final common mechanism involved in PKC- and arachidonic acid-mediated inhibitions of GABA(B)-activated K+ current.Dopamine D(2) receptor modulation of K(+) channel activity regulates excitability of nucleus accumbens neurons at different membrane potentials.Substance P initiates NFAT-dependent gene expression in spinal neurons.Escherichia coli membranes depleted of SecYEG elicit SecA-dependent ion-channel activity but lose signal peptide specificity.Regulatory mechanisms underlying the modulation of GIRK1/GIRK4 heteromeric channels by P2Y receptors.
P2860
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P2860
Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C
description
2004 nî lūn-bûn
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name
Molecular basis for the inhibi ...... ) channels by protein kinase C
@ast
Molecular basis for the inhibi ...... ) channels by protein kinase C
@en
type
label
Molecular basis for the inhibi ...... ) channels by protein kinase C
@ast
Molecular basis for the inhibi ...... ) channels by protein kinase C
@en
prefLabel
Molecular basis for the inhibi ...... ) channels by protein kinase C
@ast
Molecular basis for the inhibi ...... ) channels by protein kinase C
@en
P2093
P2860
P356
P1476
Molecular basis for the inhibi ...... ) channels by protein kinase C
@en
P2093
Asheebo Rojas
Chun Jiang
Fuxue Chen
Hailan Piao
Jinzhe Mao
Runping Wang
Xueren Wang
P2860
P304
P356
10.1073/PNAS.0304827101
P407
P50
P577
2004-01-19T00:00:00Z