Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response

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http://www.wikidata.org/entity/Q35741605
Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyDNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features.Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma.Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.Thiol-Based Potent and Selective HDAC6 Inhibitors Promote Tubulin Acetylation and T-Regulatory Cell Suppressive Function.Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor in vitro and in vivo.An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy.The Therapeutic Strategy of HDAC6 Inhibitors in Lymphoproliferative Disease
P2860

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response

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http://www.wikidata.org/entity/Q35741605
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Novel HDAC inhibitors exhibit ...... ting their anti-tumor response
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Novel HDAC inhibitors exhibit ...... ting their anti-tumor response
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type
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Novel HDAC inhibitors exhibit ...... ting their anti-tumor response
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Novel HDAC inhibitors exhibit ...... ting their anti-tumor response
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Novel HDAC inhibitors exhibit ...... ting their anti-tumor response
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Novel HDAC inhibitors exhibit ...... ting their anti-tumor response
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Novel HDAC inhibitors exhibit ...... ting their anti-tumor response
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P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932