Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.
about
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.Anti-FIRs (PUF60) auto-antibodies are detected in the sera of early-stage colon cancer patients.Adenovirus-mediated FIR demonstrated TP53-independent cell-killing effect and enhanced antitumor activity of carbon-ion beams.FIR haplodeficiency promotes splicing to pyruvate kinase M2 in mice thymic lymphoma tissues revealed by six-plex tandem mass tag quantitative proteomic analysis.Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers.
P2860
Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Haploinsufficiency of the c-my ...... gression by activating Notch1.
@ast
Haploinsufficiency of the c-my ...... gression by activating Notch1.
@en
type
label
Haploinsufficiency of the c-my ...... gression by activating Notch1.
@ast
Haploinsufficiency of the c-my ...... gression by activating Notch1.
@en
prefLabel
Haploinsufficiency of the c-my ...... gression by activating Notch1.
@ast
Haploinsufficiency of the c-my ...... gression by activating Notch1.
@en
P2093
P2860
P356
P1433
P1476
Haploinsufficiency of the c-my ...... gression by activating Notch1.
@en
P2093
Atsushi Iwama
Atsushi Kaneda
Chiaki Nakaseko
Fumio Nomura
Hideaki Shimada
Kouichi Kitamura
Mamoru Satoh
Masafumi Matsuo
Masahiko Hatano
Masaki Fukuyo
P2860
P304
P356
10.18632/ONCOTARGET.3244
P407
P577
2015-03-01T00:00:00Z