The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice.
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Parathyroid hormone receptor signaling induces bone resorption in the adult skeleton by directly regulating the RANKL gene in osteocytes.Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency.OPG Treatment Prevents Bone Loss During Lactation But Does Not Affect Milk Production or Maternal Calcium Metabolism.Osteocyte control of osteoclastogenesis.Unique Distal Enhancers Linked to the Mouse Tnfsf11 Gene Direct Tissue-Specific and Inflammation-Induced Expression of RANKL.Deletion of the Distal Tnfsf11 RL-D2 Enhancer That Contributes to PTH-Mediated RANKL Expression in Osteoblast Lineage Cells Results in a High Bone Mass Phenotype in MiceModulatory effect of 1,25-dihydroxyvitamin D 3 on IL1 β -induced RANKL, OPG, TNF α , and IL-6 expression in human rheumatoid synoviocyte MH7A.A DNA segment spanning the mouse Tnfsf11 transcription unit and its upstream regulatory domain rescues the pleiotropic biologic phenotype of the RANKL null mouse.The Role of Osteocytes in Age-Related Bone Loss.Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice.The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone.CXCL5 stimulation of RANK ligand expression in Paget's disease of bone.Parathyroid Hormone Signaling in Osteocytes
P2860
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P2860
The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The RANKL distal control regio ...... sm or lactation in adult mice.
@ast
The RANKL distal control regio ...... sm or lactation in adult mice.
@en
type
label
The RANKL distal control regio ...... sm or lactation in adult mice.
@ast
The RANKL distal control regio ...... sm or lactation in adult mice.
@en
prefLabel
The RANKL distal control regio ...... sm or lactation in adult mice.
@ast
The RANKL distal control regio ...... sm or lactation in adult mice.
@en
P2093
P2860
P356
P1476
The RANKL distal control regio ...... sm or lactation in adult mice.
@en
P2093
Carlo Galli
Charles A O'Brien
Jinhu Xiong
Melda Onal
Robert S Weinstein
Stavros C Manolagas
P2860
P304
P356
10.1210/ME.2011-1149
P577
2011-12-29T00:00:00Z