Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
about
Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1 mediated signalingPaclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death.Lactaptin induces p53-independent cell death associated with features of apoptosis and autophagy and delays growth of breast cancer cells in mouse xenografts.PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formationThe combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and BakCdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration.Apoptotic effect of hot water extract of Sanguisorba officinalis L. in human oral cancer cells.Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway.The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner.Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified.Microtubule destabilising agents: far more than just antimitotic anticancer drugs.Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53-independent necrosis via the mitochondria-associated pathway involving Bax and Bak activation.Vinblastine-induced apoptosis of melanoma cells is mediated by Ras homologous A protein (Rho A) via mitochondrial and non-mitochondrial-dependent mechanisms.Upregulation of DR5 receptor by the diaminothiazole DAT1 [4-amino-5-benzoyl-2-(4-methoxy phenyl amino) thiazole] triggers an independent extrinsic pathway of apoptosis in colon cancer cells with compromised pro and antiapoptotic proteins.Pim kinase inhibitors sensitize prostate cancer cells to apoptosis triggered by Bcl-2 family inhibitor ABT-737.Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1.Perturbing mitosis for anti-cancer therapy: is cell death the only answer?
P2860
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P2860
Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
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2008年论文
@zh-cn
name
Key role for Bak activation an ...... ptotic response to vinblastine
@ast
Key role for Bak activation an ...... ptotic response to vinblastine
@en
type
label
Key role for Bak activation an ...... ptotic response to vinblastine
@ast
Key role for Bak activation an ...... ptotic response to vinblastine
@en
prefLabel
Key role for Bak activation an ...... ptotic response to vinblastine
@ast
Key role for Bak activation an ...... ptotic response to vinblastine
@en
P2093
P2860
P1476
Key role for Bak activation an ...... ptotic response to vinblastine
@en
P2093
Elena Galitovskaya
Meenakshi Upreti
Sherri K Smart
Timothy C Chambers
P2860
P304
P356
10.1158/1535-7163.MCT-07-2299
P577
2008-07-01T00:00:00Z