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Massively parallel high-order combinatorial genetics in human cells

Massively parallel high-order combinatorial genetics in human cells

http://www.wikidata.org/entity/Q35747682

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Vertical flow array chips reliably identify cell types from single-cell mRNA sequencing experiments.Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions Synthetic lethality and cancer.Synthetic essentiality: Targeting tumor suppressor deficiencies in cancer.Bartender: a fast and accurate clustering algorithm to count barcode reads.Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity.Application of CRISPR-Cas9 Based Genome-Wide Screening Approaches to Study Cellular Signalling Mechanisms.Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance.

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P2860

Massively parallel high-order combinatorial genetics in human cells

http://www.wikidata.org/entity/Q35747682

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

@zh-hk

2015年論文

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2015年論文

@zh-tw

2015年论文

@wuu

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2015年论文

@zh-cn

name

Massively parallel high-order combinatorial genetics in human cells

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Massively parallel high-order combinatorial genetics in human cells

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type

label

Massively parallel high-order combinatorial genetics in human cells

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Massively parallel high-order combinatorial genetics in human cells

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prefLabel

Massively parallel high-order combinatorial genetics in human cells

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Massively parallel high-order combinatorial genetics in human cells

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Nature Biotechnology

P1476

Massively parallel high-order combinatorial genetics in human cells

@en

P2093

Allen A Cheng

http://www.w3.org/2001/XMLSchema#string

Gigi C G Choi

http://www.w3.org/2001/XMLSchema#string

Oliver Purcell

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Timothy K Lu

http://www.w3.org/2001/XMLSchema#string

P2860

Derivation of genetic interaction networks from quantitative phenotype data

Finding the missing heritability of complex diseases

Next-generation sequencing to generate interactome datasets

The Cancer Genome Atlas Pan-Cancer analysis project

MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer

Statistical significance for genomewide studies

Molecular roadblocks for cellular reprogramming

Combinatorial microRNA target predictions

Sequencing technologies - the next generation

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

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952-961

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scholarly article

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10.1038/NBT.3326

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9

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33

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2015-08-17T00:00:00Z

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1001233525

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26280411

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4785103

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