Increased furin activity enhances the malignant phenotype of human head and neck cancer cells
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Pushing tumor cells towards a malignant phenotype: stimuli from the microenvironment, intercellular communications and alternative roadsThe transmembrane domain of TACE regulates protein ectodomain sheddingIdentification of novel thyroid cancer-related genes and chemicals using shortest path algorithmFurin targeted drug delivery for treatment of rhabdomyosarcoma in a mouse modelActivatable oligomerizable imaging agents for photoacoustic imaging of furin-like activity in living subjectsA femtomol range FRET biosensor reports exceedingly low levels of cell surface furin: implications for the processing of anthrax protective antigenRole of c-Src activity in the regulation of gastric cancer cell migrationMatrix metalloproteases in head and neck cancer.Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasisMatrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes.Furin overexpression suppresses tumor growth and predicts a better postoperative disease-free survival in hepatocellular carcinomaEnhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6).Proprotein convertase furin regulates apoptosis and proliferation of granulosa cells in the rat ovary.Endosomal trafficking and proprotein convertase cleavage of cis Golgi protein GP73 produces marker for hepatocellular carcinoma.Molecular Validation of PACE4 as a Target in Prostate CancerInhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model.Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer.Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth.Dystroglycan Depletion Impairs Actin-Dependent Functions of Differentiated Kasumi-1 CellsOncolysis by paramyxoviruses: preclinical and clinical studies.Transgenic overexpression of the proprotein convertase furin enhances skin tumor growthThe Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion.Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3.Endo/exo-proteolysis in neoplastic progression and metastasis.TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.Enhanced UV-induced skin carcinogenesis in transgenic mice overexpressing proprotein convertases.Inhibition of proprotein convertases: approaches to block squamous carcinoma development and progression.Therapeutic uses of furin and its inhibitors: a patent review.Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas.PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neovascularisation.A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.The proprotein convertase furin in tumour progression.Human head and neck squamous cell carcinoma cells are both targets and effectors for the angiogenic cytokine, VEGF.Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence RequirementNovel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers.Characterization and expression of proprotein convertases in CHO cells: Efficient proteolytic maturation of human bone morphogenetic protein-7.
P2860
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P2860
Increased furin activity enhances the malignant phenotype of human head and neck cancer cells
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Increased furin activity enhan ...... man head and neck cancer cells
@ast
Increased furin activity enhan ...... man head and neck cancer cells
@en
type
label
Increased furin activity enhan ...... man head and neck cancer cells
@ast
Increased furin activity enhan ...... man head and neck cancer cells
@en
prefLabel
Increased furin activity enhan ...... man head and neck cancer cells
@ast
Increased furin activity enhan ...... man head and neck cancer cells
@en
P2093
P2860
P1476
Increased furin activity enhan ...... man head and neck cancer cells
@en
P2093
Andres Klein-Szanto
Daniel E Bassi
Haleh Mahloogi
Ricardo Lopez De Cicco
P2860
P304
P356
10.1016/S0002-9440(10)63838-2
P407
P577
2003-02-01T00:00:00Z