SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice. - Wikidata - wikimedia - TriplyDB

SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice.

SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice.

http://www.wikidata.org/entity/Q35749349

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Induction of ErbB-3 expression by alpha6beta4 integrin contributes to tamoxifen resistance in ERbeta1-negative breast carcinomas Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells Growth factors, nutrient signaling, and cardiovascular aging Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging Sirt1 deficiency attenuates spermatogenesis and germ cell function Identification of a novel pathway that selectively modulates apoptosis of breast cancer cells.Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling.Dual role of SIRT1 in UVB-induced skin tumorigenesis.Sirtuin1 (Sirt1) promotes cortical bone formation by preventing β-catenin sequestration by FoxO transcription factors in osteoblast progenitors.Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.An epigenetic perspective on the free radical theory of development Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model.Sirt1 inhibits akt2-mediated porcine adipogenesis potentially by direct protein-protein interaction.SIRT1 catalytic activity has little effect on tumor formation and metastases in a mouse model of breast cancer.The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells.Sirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injury Sirt1 restrains lung inflammasome activation in a murine model of sepsis.SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer An Ideal PPAR Response Element Bound to and Activated by PPARα.Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions.SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice.SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression.Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses.ZBTB20 is required for anterior pituitary development and lactotrope specification SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens.SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action.SIRT1 deacetylates FOXA2 and is critical for Pdx1 transcription and β-cell formation.Metabolic defects provide a spark for the epigenetic switch in cancer.Sirtuin 1 in immune regulation and autoimmunity.Sentinel lymph node in endometrial cancer: a review.The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases.Sirtuin 1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions.Nicotinamide Mononucleotide, an NAD+ Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1-Dependent Manner.In vivo RNA interference models of inducible and reversible Sirt1 knockdown in kidney cells.

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SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice.

http://www.wikidata.org/entity/Q35749349

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

SirT1 modulates the estrogen-i ...... ment of mammary gland in mice.

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SirT1 modulates the estrogen-i ...... ment of mammary gland in mice.

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type

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SirT1 modulates the estrogen-i ...... ment of mammary gland in mice.

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SirT1 modulates the estrogen-i ...... ment of mammary gland in mice.

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SirT1 modulates the estrogen-i ...... ment of mammary gland in mice.

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SirT1 modulates the estrogen-i ...... ment of mammary gland in mice.

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Breast Cancer Research

P1476

SirT1 modulates the estrogen-i ...... pment of mammary gland in mice

@en

P2093

Brian P Rubin

http://www.w3.org/2001/XMLSchema#string

Carol Ware

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Grace K Rajendran

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Hongzhe Li

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Yansong Gu

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P2860

Key stages of mammary gland development: molecular mechanisms involved in the formation of the embryonic mammary gland.

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Sir2 blocks extreme life-span extension.

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae.

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17201918

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1851382

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