Enhanced T-cell reconstitution by hematopoietic progenitors expanded ex vivo using the Notch ligand Delta1
about
Tumor immunotherapy across MHC barriers using allogeneic T-cell precursorsEngineering approaches for regeneration of T lymphopoiesisAdvances in umbilical cord blood manipulation-from niche to bedsideProteins and small molecules for cellular regenerative medicineNotch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymusAcute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.Ex vivo expansion of human hematopoietic stem and progenitor cells.Activation of Notch signaling during ex vivo expansion maintains donor muscle cell engraftmentDefined, serum-free conditions for in vitro culture of primary human T-ALL blasts.Increasing hematopoietic stem cell yield to develop mice with human immune systems.Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man.Clinical strategies to enhance posttransplant immune reconstitution.NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.Notch signaling in hematopoietic cell transplantation and T cell alloimmunity.Notch signaling in the hematopoietic system.Emerging concepts in haematopoietic cell transplantation.Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34+ cord blood hematopoietic progenitor cells.Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling.Risk factors and options to improve engraftment in unrelated cord blood transplantationCell-surface Notch1 expression identifies a primitive phenotype within CD34+ CD38- haematopoietic cells.Posttransplant chimeric antigen receptor therapy.
P2860
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P2860
Enhanced T-cell reconstitution by hematopoietic progenitors expanded ex vivo using the Notch ligand Delta1
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Enhanced T-cell reconstitution ...... using the Notch ligand Delta1
@ast
Enhanced T-cell reconstitution ...... using the Notch ligand Delta1
@en
type
label
Enhanced T-cell reconstitution ...... using the Notch ligand Delta1
@ast
Enhanced T-cell reconstitution ...... using the Notch ligand Delta1
@en
prefLabel
Enhanced T-cell reconstitution ...... using the Notch ligand Delta1
@ast
Enhanced T-cell reconstitution ...... using the Notch ligand Delta1
@en
P2093
P2860
P1433
P1476
Enhanced T-cell reconstitution ...... using the Notch ligand Delta1
@en
P2093
Barbara Varnum-Finney
Irwin D Bernstein
Mari H Dallas
Paul J Martin
P2860
P304
P356
10.1182/BLOOD-2006-08-039842
P407
P577
2007-01-09T00:00:00Z