Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK - Wikidata - wikimedia - TriplyDB

Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK

Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK

http://www.wikidata.org/entity/Q35751980

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Phytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancers Cancer prevention with promising natural products: mechanisms of action and molecular targets Low-dose curcumin stimulates proliferation, migration and phagocytic activity of olfactory ensheathing cells Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment Induction of apoptosis in human breast cancer cells via caspase pathway by vernodalin isolated from Centratherum anthelminticum (L.) seeds Mitochondrial-targeted curcuminoids: a strategy to enhance bioavailability and anticancer efficacy of curcumin Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cells Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line.Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts.Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo.NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts.Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.Cellular responses to Cisplatin-induced DNA damage.Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria.Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma.EGF up-regulates miR-31 through the C/EBPβ signal cascade in oral carcinoma.Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties.The multifaceted role of curcumin in cancer prevention and treatment.Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas.Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway Potential application of curcumin and its analogues in the treatment strategy of patients with primary epithelial ovarian cancer.Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs.Visible light is a better co-inducer of apoptosis for curcumin-treated human melanoma cells than UVA.Design and synthesis of C3-pyrazole/chalcone-linked beta-carboline hybrids: antitopoisomerase I, DNA-interactive, and apoptosis-inducing anticancer agents.Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin.Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers.Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation.Apoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo.Reproductive effects of a pegylated curcumin.EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrum Curcumin induces G2/M arrest and triggers apoptosis via FoxO1 signaling in U87 human glioma cells Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell death Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells Integrin α6/Akt/Erk signaling is essential for human breast cancer resistance to radiotherapy.

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Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK

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Karuppaiyah Selvendiran

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Liyue Tong

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Nathan M Weir

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Periannan Kuppusamy

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Shilpa Vishwanath

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Shrikant Anant

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Susheela Tridandapani

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P2860

The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis

Mitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epithelium

Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line.

Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl

Pharmacology of Curcuma longa

Curcumin prevents adriamycin nephrotoxicity in rats

MAP kinase pathways.

Progress in cancer chemoprevention: development of diet-derived chemopreventive agents.

Traditional Indian systems of medicine.

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

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Murugesan V S Rajaram

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1852522

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