The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth.
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RET modulates cell adhesion via its cleavage by caspase in sympathetic neuronsA GRFa2/Prop1/stem (GPS) cell niche in the pituitaryMolecular control of the neural crest and peripheral nervous system developmentDirect promoter induction of p19Arf by Pit-1 explains the dependence receptor RET/Pit-1/p53-induced apoptosis in the pituitary somatotroph cellsDiminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches.Research resource: A genome-wide study identifies potential new target genes for POU1F1Neuroendocrine inhibition of glucose production and resistance to cancer in dwarf mice.RET PLCγ phosphotyrosine binding domain regulates Ca2+ signaling and neocortical neuronal migration.Dose-dependent dual role of PIT-1 (POU1F1) in somatolactotroph cell proliferation and apoptosisDependence receptors: mechanisms of an announced death.Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene.Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity.Targeting MAPK (Ras/ERK) and PI3K/Akt pathways in pituitary tumorigenesis.Key signaling molecules in pituitary tumors.Targeting neurotrophin-3 and its dependence receptor tyrosine kinase receptor C: a new antitumoral strategy.Central role of RET in thyroid cancer.The AIP (aryl hydrocarbon receptor-interacting protein) gene and its relation to the pathogenesis of pituitary adenomas.Dependence receptors and colorectal cancer.Regulation of pituitary stem cells by epithelial to mesenchymal transition events and signaling pathways.Stem/progenitor cells in pituitary organ homeostasis and tumourigenesis.The GDNF Family: A Role in Cancer?
P2860
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P2860
The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth.
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
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2007年论文
@zh-cn
name
The dependence receptor Ret in ...... hway, preventing tumor growth.
@ast
The dependence receptor Ret in ...... hway, preventing tumor growth.
@en
type
label
The dependence receptor Ret in ...... hway, preventing tumor growth.
@ast
The dependence receptor Ret in ...... hway, preventing tumor growth.
@en
prefLabel
The dependence receptor Ret in ...... hway, preventing tumor growth.
@ast
The dependence receptor Ret in ...... hway, preventing tumor growth.
@en
P2093
P2860
P50
P356
P1433
P1476
The dependence receptor Ret in ...... thway, preventing tumor growth
@en
P2093
Carlos Dieguez
Carmen Cañibano
Frank Costantini
Maria Grazia Borrello
Montse Garcia-Lavandeira
P2860
P304
P356
10.1038/SJ.EMBOJ.7601636
P407
P577
2007-03-22T00:00:00Z