Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. - Wikidata - wikimedia - TriplyDB

Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues.

Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues.

http://www.wikidata.org/entity/Q35754523

about

The novel sorting nexin SNX33 interferes with cellular PrP formation by modulation of PrP shedding α-Cleavage of cellular prion protein The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa Brain immune interactions and air pollution: macrophage inhibitory factor (MIF), prion cellular protein (PrP(C)), Interleukin-6 (IL-6), interleukin 1 receptor antagonist (IL-1Ra), and interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum diff The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP.Cleavage of the amino terminus of the prion protein by reactive oxygen species.Clearance and prevention of prion infection in cell culture by anti-PrP antibodies.Unexpected tolerance of alpha-cleavage of the prion protein to sequence variations Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophrenia Endogenous proteolytic cleavage of disease-associated prion protein to produce C2 fragments is strongly cell- and tissue-dependent.Allelic origin of protease-sensitive and protease-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease with the P102L mutation.A plausible function of the prion protein: conjectures and a hypothesis.Influence of Mabs on PrP(Sc) formation using in vitro and cell-free systems Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain.Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE).Prion infection impairs the cellular response to oxidative stress A naturally occurring C-terminal fragment of the prion protein (PrP) delays disease and acts as a dominant-negative inhibitor of PrPSc formation.Ubiquitin-specific protease 14 modulates degradation of cellular prion protein Interaction between Shadoo and PrP Affects the PrP-Folding Pathway Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice.Prion infection of muscle cells in vitro Cellular prion protein regulates its own α-cleavage through ADAM8 in skeletal muscle.PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells A novel phenotype of sporadic Creutzfeldt-Jakob disease.Morphine Withdrawal Modifies Prion Protein Expression in Rat Hippocampus Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivo The prion protein preference of sporadic Creutzfeldt-Jakob disease subtypes.Cellular prion protein: from physiology to pathology.Separate mechanisms act concurrently to shed and release the prion protein from the cell.Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.Prion protein scrapie and the normal cellular prion protein Anti-PrP Mab 6D11 suppresses PrP(Sc) replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo Interactions of prion protein with intracellular proteins: so many partners and no consequences?Prion processing: a double-edged sword?Proteolytic processing of the prion protein in health and disease.Altered prion protein glycosylation in the aging mouse brain.Prion protein "gamma-cleavage": characterizing a novel endoproteolytic processing event.

P2860

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P2860

Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues.

http://www.wikidata.org/entity/Q35754523

description

1998 nî lūn-bûn

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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1998年论文

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1998年论文

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Endogenous proteolytic cleavag ...... neural and non-neural tissues.

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Endogenous proteolytic cleavag ...... neural and non-neural tissues.

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Endogenous proteolytic cleavag ...... neural and non-neural tissues.

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Endogenous proteolytic cleavag ...... neural and non-neural tissues.

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Endogenous proteolytic cleavag ...... neural and non-neural tissues.

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Endogenous proteolytic cleavag ...... neural and non-neural tissues.

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The American Journal of Pathology

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Endogenous proteolytic cleavag ...... neural and non-neural tissues.

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P2860

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

Fatal familial insomnia, a prion disease with a mutation at codon 178 of the prion protein gene

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

Localization of a human gene homologous to the PrP gene on the p arm of chromosome 20 and detection of PrP-related antigens in normal human brain

Identification of candidate proteins binding to prion protein

Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein.

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease.

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

P304

1561-1572

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10.1016/S0002-9440(10)65744-6

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P433

5

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P478

153

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1998-11-01T00:00:00Z

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P698

9811348

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P921

Prion protein family

P932

1853409

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