A transgenic mouse model for human autosomal dominant cataract - Wikidata - wikimedia - TriplyDB

A transgenic mouse model for human autosomal dominant cataract

A transgenic mouse model for human autosomal dominant cataract

http://www.wikidata.org/entity/Q35757577

about

Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataract Crystal Structure of an Activated Variant of Small Heat Shock Protein Hsp16.5 Interactions between small heat shock protein alpha-crystallin and galectin-related interfiber protein (GRIFIN) in the ocular lens In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death AlphaA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice.Aldo-keto reductases in the eye.Cat-Map: putting cataract on the map Molecular mechanism of formation of cortical opacity in CRYAAN101D transgenic mice.Mechanism of cataract formation in alphaA-crystallin Y118D mutation.The common modification in alphaA-crystallin in the lens, N101D, is associated with increased opacity in a mouse model.Activation of unfolded protein response in transgenic mouse lenses.Mutation analysis of two families with inherited congenital cataracts.Chemical modulation of the chaperone function of human alphaA-crystallin.Phenotype of cardiomyopathy in cardiac-specific heat shock protein B8 K141N transgenic mouse.Differential role of arginine mutations on the structure and functions of α-crystallin.Structure and mechanism of protein stability sensors: chaperone activity of small heat shock proteins.Lens crystallin modifications and cataract in transgenic mice overexpressing acylpeptide hydrolase.Small heat-shock proteins: important players in regulating cellular proteostasis.Effect of Geranylgeranylacetone on Ultraviolet Radiation Type B-Induced Cataract in Heat-Shock Transcription Factor 1 Heterozygous Mouse.Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human αB-crystallin.Hydroimidazolone modification of human alphaA-crystallin: Effect on the chaperone function and protein refolding ability.Role of cysteine residues in the enhancement of chaperone function in methylglyoxal-modified human alpha A-crystallin.AP-2α is required after lens vesicle formation to maintain lens integrity.Real-time heterogeneous protein-protein interaction between αA-crystallin N-terminal mutants and αB-crystallin using quartz crystal microbalance (QCM).

P2860

Q24297386-14CBE808-E355-48C4-BE28-7646D6F5C734 Q27679512-3C4B1EC6-84AC-4E5D-94FF-9886AEB18E2D Q28513843-F0FA221D-C67C-4BF2-82C8-624482485BF6 Q28538157-D359A22B-89DC-4A12-BEE4-648EF52A162B Q28591145-E5459EF7-2E84-40DD-B582-24E581907FC8 Q33484430-3958751A-5E1D-487C-9D41-F157A61FF203 Q33984794-1832D572-2793-4EBE-A072-97FBBE26CC89 Q34248597-01FD4856-8D6C-41FD-950D-2C9694F37984 Q34341725-A1173252-8B34-44C8-892D-D812B5B2705D Q34402815-6EBE6806-8198-4945-8204-C632151B0F6B Q34719735-479C4EBD-E6F6-41B9-BCF1-463DFB15F33F Q34824098-E191D8CA-5328-4878-9EEB-C3B6C1D7C8A4 Q35919805-F3452E12-0F9F-4D36-983C-E953A5CABCDA Q36587179-591271F2-3683-462E-9FC6-BFCBB92BBC17 Q36724928-1B54F0E9-AF27-492D-9C2D-F1481035D606 Q37021424-0D47B41C-22D8-457C-ABDF-9544753E9A96 Q37424170-75AA412F-81B5-427F-AF9D-75872CA80993 Q37691605-DED30F6E-A62B-4C33-80C3-E3A1D5E19545 Q38263437-887D1A80-2429-4E22-9B4C-DAB423BBB08C Q39299545-B1C47527-71AF-4713-8FB8-315FF136E4BA Q41868198-ACBAA6F7-B8A3-4707-A5EB-86D4741D0D87 Q41911286-60D89EA8-D24E-4D4A-B968-89FFB2874E47 Q42935346-EF21F235-2E84-4A5D-A209-AF88ED9989C2 Q50668949-0B6E8ADB-C454-4114-AE7C-1AD98F833405 Q53604350-A1AC434A-E3E9-426D-B151-256CB1625A4F

P2860

A transgenic mouse model for human autosomal dominant cataract

http://www.wikidata.org/entity/Q35757577

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

A transgenic mouse model for human autosomal dominant cataract

@ast

A transgenic mouse model for human autosomal dominant cataract

@en

type

label

A transgenic mouse model for human autosomal dominant cataract

@ast

A transgenic mouse model for human autosomal dominant cataract

@en

prefLabel

A transgenic mouse model for human autosomal dominant cataract

@ast

A transgenic mouse model for human autosomal dominant cataract

@en

P1433

Q35757577-8F5DB5D8-93B1-451E-A739-031B750EC5EF

P1476

Q35757577-B6D64349-0897-48C1-B071-148EA28399C5

P2093

Q35757577-16A18BCB-D89C-44DE-A04B-A5253984568D

Q35757577-1ABF5D4C-A3FA-4684-8C9A-922B2EC2ED86

Q35757577-5503DDC3-66FB-4C7A-BD2F-C8D5EACCA6B6

P2860

Q35757577-033E94FF-C03E-474B-9121-48EED893191F

Q35757577-0B2FAF8D-EA17-409A-97C2-A56FEC53ED8E

Q35757577-19C9BCAC-6AC3-4544-B873-548A311807F1

Q35757577-1ED58352-F94D-475E-B022-5890D43CD38A

Q35757577-1F2BEC5E-7AEB-4087-A99E-E68871AC5B93

Q35757577-2AB2234B-8F40-4D6E-B424-97DD1EC38558

Q35757577-3BF05967-1EF3-4E21-A578-D9A6876CBC35

Q35757577-3EEF66B1-65EE-424E-A29B-DFB5BFB576E4

Q35757577-4AC44F8A-3DFB-4CA7-BBEC-1E69A09AE65B

Q35757577-5BEE49AA-06FE-4EB4-844E-8DEC6D2FA0E0

P304

Q35757577-33A6F63F-D37C-4F90-A365-B2282137C2E9

P31

Q35757577-EFD9E390-6D7C-406F-856B-92DDCCDF383B

P356

Q35757577-95AE081E-AE24-4A57-8BC1-97D6A801C8B0

P407

Q35757577-79105ACA-E068-4D93-A42F-D52368BE62C0

P433

Q35757577-74980F99-CC39-4E3A-B337-15B8197D44A0

P478

Q35757577-0A7D4126-AAE4-446F-B6A2-10DEBD3DF1CF

P577

Q35757577-92BA0F67-F9A5-40A4-AB35-E38313108F45

P5875

Q35757577-3C05E380-1BB3-477F-A197-BB17600C10FE

P698

Q35757577-E07F086F-2E2B-4282-9CE5-3ADC5CB852CD

P932

Q35757577-7DA627C8-579B-4B0E-A5B8-3E066F4A9686

P356

P1433

Investigative Ophthalmology & Visual Science

P1476

A transgenic mouse model for human autosomal dominant cataract

@en

P2093

Cheng-Da Hsu

http://www.w3.org/2001/XMLSchema#string

J Mark Petrash

http://www.w3.org/2001/XMLSchema#string

Steven Kymes

http://www.w3.org/2001/XMLSchema#string

P2860

Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q

Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA

A juvenile-onset, progressive cataract locus on chromosome 3q21-q22 is associated with a missense mutation in the beaded filament structural protein-2

Autosomal-dominant congenital cataract associated with a deletion mutation in the human beaded filament protein gene BFSP2

Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

Alpha-crystallin can function as a molecular chaperone

The cardiomyopathy and lens cataract mutation in alphaB-crystallin alters its protein structure, chaperone activity, and interaction with intermediate filaments in vitro.

Development- and differentiation-dependent reorganization of intermediate filaments in fiber cells.

Molecular architecture of the lens fiber cell basal membrane complex.

The interrelationship of lens anatomy and optical quality. II. Primate lenses.

P304

2036-2044

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1167/IOVS.05-0524

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

47

http://www.w3.org/2001/XMLSchema#string

P577

2006-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7142080

http://www.w3.org/2001/XMLSchema#string

P698

16639013

http://www.w3.org/2001/XMLSchema#string

P932

1855087

http://www.w3.org/2001/XMLSchema#string