Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
about
The kinetic effects on thymidine kinase 2 by enzyme-bound dTTP may explain the mitochondrial side effects of antiviral thymidine analogsMutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1.Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondriaA novel mechanism of selectivity against AZT by the human mitochondrial DNA polymerase.Effect of AZT on thymidine phosphorylation in cultured H9c2, U-937, and Raji cell lines.Effects of zidovudine and stavudine on mitochondrial DNA of differentiating 3T3-F442a cells are not associated with imbalanced deoxynucleotide pools.Mitochondrial DNA impairment in nucleoside reverse transcriptase inhibitor-associated cardiomyopathyLong-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction.Functional characterization of drug uptake and metabolism in the heart.Mechanistic interplay among the M184I HIV-1 reverse transcriptase mutant, the central polypurine tract, cellular dNTP concentrations and drug sensitivity.The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes.Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
P2860
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P2860
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
@ast
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
@en
type
label
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
@ast
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
@en
prefLabel
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
@ast
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
@en
P2093
P2860
P356
P1476
Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart
@en
P2093
Alice T Bentley
Darcy D LaClair
Delia Susan-Resiga
Matthew D Lynx
P2860
P304
P356
10.1128/AAC.01227-06
P407
P50
P577
2007-01-12T00:00:00Z