Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy.
about
Origins of the Vertebrate Erythro/Megakaryocytic SystemThe megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesisThrombopoietin.Historical review: megakaryopoiesis and thrombopoiesisGene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.Preliminary nonclinical toxicity, pharmacokinetics, and pharmacodynamics of ALXN4100TPO, a thrombopoietin receptor agonist, in CD2F1 mice.The biology of thrombopoietin and thrombopoietin receptor agonists.Thrombocytopenia-Platelet Support or Growth Factors?Thrombopoietin Receptor Agonist Mitigates Hematopoietic Radiation Syndrome and Improves Survival after Whole-Body Ionizing Irradiation Followed by Wound TraumaErythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling.Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin.Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory siteThe molecular and cellular biology of thrombopoietin: the primary regulator of platelet production.Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietinH2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/plateletsThrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.Targeting c-Mpl for revival of human immunodeficiency virus type 1-induced hematopoietic inhibition when CD34+ progenitor cells are re-engrafted into a fresh stromal microenvironment in vivo.Novel pathways to erythropoiesis induced by dimerization of intracellular C-Mpl in human hematopoietic progenitors.Mouse models of diseases of megakaryocyte and platelet homeostasis.Evolving insights into the synergy between erythropoietin and thrombopoietin and the bipotent erythroid/megakaryocytic progenitor cell.Thrombopoietin expands hematopoietic stem cells after transplantation.Regulation of polymorphonuclear cell activation by thrombopoietin.A new role of thrombopoietin enhancing ex vivo expansion of endothelial precursor cells derived from AC133-positive cells.The glycan domain of thrombopoietin (TPO) acts in trans to enhance secretion of the hormone and other cytokines.Megakaryocytic Maturation is Regulated by Maintaining a Balance Against Cytokine Induced-cell Proliferation: Steel Factor Retards Thrombopoietin-induced Megakaryocytic Differentiation While Synergistically Stimulating Mitogenesis; Hematopoiesis.Role for C-MPL and its ligand thrombopoietin in early hematopoiesis.Differential effects of recombinant thrombopoietin and bone marrow stromal-conditioned media on neonatal versus adult megakaryocytes.Relationship of different platelet response criteria and patient outcomes in a romiplostim myelodysplastic syndromes trial.Thrombopoietin modulates the proliferation, migration and cytokine profile of decidual cell subsets during early gestation.Effects of thrombopoietin on the proliferation and differentiation of primitive and mature haemopoietic progenitor cells in cord blood.Quantitative analysis of thrombopoietin receptors on human megakaryocytes.Leukemic mature B-cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis.
P2860
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P2860
Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Thrombopoietin expands erythro ...... fter myelosuppressive therapy.
@ast
Thrombopoietin expands erythro ...... fter myelosuppressive therapy.
@en
type
label
Thrombopoietin expands erythro ...... fter myelosuppressive therapy.
@ast
Thrombopoietin expands erythro ...... fter myelosuppressive therapy.
@en
prefLabel
Thrombopoietin expands erythro ...... fter myelosuppressive therapy.
@ast
Thrombopoietin expands erythro ...... fter myelosuppressive therapy.
@en
P2093
P2860
P356
P1476
Thrombopoietin expands erythro ...... fter myelosuppressive therapy.
@en
P2093
A Grossmann
J W Forstrom
K H Sprugel
K Kaushansky
M C Bailey
T Papayannopoulou
V C Broudy
P2860
P304
P356
10.1172/JCI118210
P407
P577
1995-09-01T00:00:00Z