Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis - Wikidata - wikimedia - TriplyDB

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

http://www.wikidata.org/entity/Q35764554

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Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures Polymorphisms in the 5' flank of COL1A1 gene and osteoporosis: meta-analysis of published studies Wnt modulators in the biotech pipeline High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone New sequence variants associated with bone mineral density Control of bone formation by the serpentine receptor Frizzled-9 Evidence for pleiotropic factors in genetics of the musculoskeletal system European bone mineral density loci are also associated with BMD in East-Asian populations Genetic studies in osteoporosis--the end of the beginning An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo Association between LRP5 polymorphism and bone mineral density: a Bayesian meta-analysis Association analysis of WNT10B with bone mass and structure among individuals of African ancestry Discovery properties of genome-wide association signals from cumulatively combined data sets.Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.Association of LRP5 genotypes with osteoporosis in Tunisian post-menopausal women The emerging role of serotonin (5-hydroxytryptamine) in the skeleton and its mediation of the skeletal effects of low-density lipoprotein receptor-related protein 5 (LRP5).Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture.VKORC1 common variation and bone mineral density in the Third National Health and Nutrition Examination Survey WNT3A gene polymorphisms are associated with bone mineral density variation in postmenopausal mestizo women of an urban Mexican population: findings of a pathway-based high-density single nucleotide screening.Association study of polymorphisms in the SOST gene region and parameters of bone strength and body composition in both young and elderly men: data from the Odense Androgen Study.Replication of previous genome-wide association studies of bone mineral density in premenopausal American women.Genetic determinants of osteoporosis: common bases to cardiovascular diseases?Association of a functional variant in the Wnt co-receptor LRP6 with early onset ileal Crohn's disease Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.Contribution of a common variant in the promoter of the 1-α-hydroxylase gene (CYP27B1) to fracture risk in the elderly.A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene and bone mineral density in Japanese male workers Common polymorphism in the LRP5 gene may increase the risk of bone fracture and osteoporosis.The genetics of bone loss: challenges and prospects Polymorphism of the low-density lipoprotein receptor-related protein 5 gene and fracture risk Genetic analysis of the relationship between bone mineral density and low-density lipoprotein receptor-related protein 5 gene polymorphisms.Associations of APOE gene polymorphisms with bone mineral density and fracture risk: a meta-analysis.Identification of the first deletion in the LRP5 gene in a patient with autosomal dominant osteopetrosis type I IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study.Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects.

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Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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type

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Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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prefLabel

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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JAMA.299.11.1277

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Journal of the American Medical Association

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Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

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Barbara Obermayer-Pietsch

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Bente L Langdahl

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David M Reid

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Fiona E A McGuigan

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Francois Rousseau

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GENOMOS Study

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Huibert A P Pols

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Joyce B J van Meurs

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Kristina Akesson

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Kurt Weber

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P2860

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study.

LDL-receptor-related proteins in Wnt signal transduction

Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

Structure of the LDL receptor extracellular domain at endosomal pH

A New Statistical Method for Haplotype Reconstruction from Population Data

Measuring inconsistency in meta-analyses

Meta-analysis in clinical trials

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1277-1290

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scholarly article

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10.1001/JAMA.299.11.1277

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11

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299

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Fernando Rivadeneira

Göran Hallmans

André Uitterlinden

Susana Balcells

Magnus K Karlsson

Douglas P. Kiel

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2008-03-01T00:00:00Z

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5503561

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18349089

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3282142

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