Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid.
about
Complement system activation and endothelial dysfunction in patients with age-related macular degeneration (AMD): possible relationship between AMD and atherosclerosisThe stereotypical molecular cascade in neovascular age-related macular degeneration: the role of dynamic reciprocitySystemic complement activation in age-related macular degenerationGenetic markers and biomarkers for age-related macular degeneration.Complement factor H: using atomic resolution structure to illuminate disease mechanisms.Overactivation of Complement Alternative Pathway in Postpartum Atypical Hemolytic Uremic Syndrome Patients with Renal Involvement.Complement factor h is critical in the maintenance of retinal perfusion.Animals as models of age-related macular degeneration: an imperfect measure of the truth.Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study.Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular healthIdentification of acidic pH-dependent ligands of pentameric C-reactive protein.Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathwayExpression profiles of nestin and synemin in reactive astrocytes and Müller cells following retinal injury: a comparison with glial fibrillar acidic protein and vimentinThe membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning.Complement component C5a activates ICAM-1 expression on human choroidal endothelial cellsInteraction of complement factor h and fibulin3 in age-related macular degenerationAssociation between CFH Y402H polymorphism and age related macular degeneration in North Indian cohort.Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.The local complement activation on vascular bed of patients with systemic sclerosis: a hypothesis-generating studyComplement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levelsCFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye.Age-Related Macular Degeneration: A Disease of Systemic or Local Complement Dysregulation?Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtypeUnderstanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex.How does the macula protect itself from oxidative stress?Plasma levels of complement proteins from the alternative pathway in patients with age-related macular degeneration are independent of Complement Factor H Tyr⁴⁰²His polymorphism.Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera.Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration.Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variantsY402H polymorphism of complement factor H affects binding affinity to C-reactive protein.The role of the immune response in age-related macular degenerationMolecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration.C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degenerationC-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration.Translational mini-review series on complement factor H: structural and functional correlations for factor H.Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro.CFH Y402H polymorphism and the complement activation product C5a: effects on NF-κB activation and inflammasome gene regulationMolecular pathology of age-related macular degeneration
P2860
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P2860
Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Individuals homozygous for the ...... levels of CRP in the choroid.
@ast
Individuals homozygous for the ...... levels of CRP in the choroid.
@en
type
label
Individuals homozygous for the ...... levels of CRP in the choroid.
@ast
Individuals homozygous for the ...... levels of CRP in the choroid.
@en
prefLabel
Individuals homozygous for the ...... levels of CRP in the choroid.
@ast
Individuals homozygous for the ...... levels of CRP in the choroid.
@en
P2093
P2860
P356
P1476
Individuals homozygous for the ...... levels of CRP in the choroid.
@en
P2093
D H Anderson
G S Hageman
L V Johnson
M J Radeke
P T Johnson
P2860
P304
17456-17461
P356
10.1073/PNAS.0606234103
P407
P577
2006-11-01T00:00:00Z