Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

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Association of a BACE1 Gene Polymorphism with Parkinson's Disease in a Norwegian Population.

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Q42178133-5594A58B-CDF3-4AA9-AB16-00258F29FFCA

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Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

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http://www.wikidata.org/entity/Q35772659

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2015 nî lūn-bûn

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2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

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2015年论文

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2015年论文

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2015年论文

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name

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

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Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

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label

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

@ast

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

@en

prefLabel

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

@ast

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

@en

P1476

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

@en

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Chang E Yu

http://www.w3.org/2001/XMLSchema#string

Cyrus P Zabetian

http://www.w3.org/2001/XMLSchema#string

Elaine R Peskind

http://www.w3.org/2001/XMLSchema#string

Jing Zhang

http://www.w3.org/2001/XMLSchema#string

Lynn M Bekris

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Thomas J Montine

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P2860

S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10

Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.

[alpha]-Secretase ADAM10 as well as [alpha]APPs is reduced in platelets and CSF of Alzheimer disease patients

A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex

Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates

Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex

Tau protein, the paired helical filament and Alzheimer's disease

Identification of distinct gamma-secretase complexes with different APH-1 variants

Pen-2 is incorporated into the gamma-secretase complex through binding to transmembrane domain 4 of presenilin 1

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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936-944

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scholarly article

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10.1002/MDS.26172

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English

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http://www.w3.org/2001/XMLSchema#string

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James B Leverenz

Debby W Tsuang

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2015-03-24T00:00:00Z

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25808939

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cerebrospinal fluid

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4478197

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Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

about

P2860

P2860

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932