Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen.
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Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer MedicineKeep-ING balance: tumor suppression by epigenetic regulationGenome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.Breast cancer associated with neurofibromatosis type 1: a case series and review of the literatureING5 suppresses breast cancer progression and is regulated by miR-24The NF1 somatic mutational landscape in sporadic human cancers.Type II transmembrane serine protease gene variants associate with breast cancer.The NF1 gene revisited - from bench to bedside.Essential gene profiles in breast, pancreatic, and ovarian cancer cells.Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq dataOptimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens.Mining gene expression signature for the detection of pre-malignant melanocytes and early melanomas with risk for metastasisCohesin is required for activation of MYC by estradiol.Mammary glands exhibit molecular laterality and undergo left-right asymmetric ductal epithelial growth in MMTV-cNeu mice.Peptide Lv augments L-type voltage-gated calcium channels through vascular endothelial growth factor receptor 2 (VEGFR2) signaling.ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53Enhanced expression of cohesin loading factor NIPBL confers poor prognosis and chemotherapy resistance in non-small cell lung cancerProgress in breast cancer research.Integrative Analysis of Response to Tamoxifen Treatment in ER-Positive Breast Cancer Using GWAS Information and Transcription ProfilingThe Ras-like protein R-Ras2/TC21 is important for proper mammary gland development.Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancerIn Vitro-Pooled shRNA Screening to Identify Determinants of Radiosensitivity.Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2 and BRCAX, but not BRCA1 familial breast cancers.Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver.Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactionsNF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPTAn inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response.Models and Mechanisms of Acquired Antihormone Resistance in Breast Cancer: Significant Clinical Progress Despite Limitations.Derailed estrogen signaling and breast cancer: an authentic couple.Postmenopausal hormone therapy and colorectal cancer risk in relation to somatic KRAS mutation status among older womenDistinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population.Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition.Pan-cancer analyses of the nuclear receptor superfamilySystems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity.In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signalingVariability in functional p53 reactivation by PRIMA-1(Met)/APR-246 in Ewing sarcoma.Understanding the language of Lys36 methylation at histone H3.Neurofibromatosis type I with breast cancer: not only for women!Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease.Using titanium complexes to defeat cancer: the view from the shoulders of titans.
P2860
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P2860
Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Genome-wide functional screen ...... ting sensitivity to tamoxifen.
@ast
Genome-wide functional screen ...... ting sensitivity to tamoxifen.
@en
type
label
Genome-wide functional screen ...... ting sensitivity to tamoxifen.
@ast
Genome-wide functional screen ...... ting sensitivity to tamoxifen.
@en
prefLabel
Genome-wide functional screen ...... ting sensitivity to tamoxifen.
@ast
Genome-wide functional screen ...... ting sensitivity to tamoxifen.
@en
P2093
P2860
P50
P356
P1476
Genome-wide functional screen ...... ting sensitivity to tamoxifen.
@en
P2093
Ana M Mendes-Pereira
Costas Mitsopoulos
David Sims
Ioannis Assiotis
Iwanka Kozarewa
Jarle Hakas
Kerry Fenwick
Tim Dexter
P2860
P304
P356
10.1073/PNAS.1018872108
P407
P577
2011-04-11T00:00:00Z