Screening the receptorome to discover the molecular targets for plant-derived psychoactive compounds: a novel approach for CNS drug discovery.
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ChemProt: a disease chemical biology databaseStudies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine releaseDrug Repurposing Is a New Opportunity for Developing Drugs against Neuropsychiatric DisordersDREADDs: novel tools for drug discovery and developmentMapping the genome of Plasmodium falciparum on the drug-like chemical space reveals novel anti-malarial targets and potential drug leadsApplication of computational systems biology to explore environmental toxicity hazardsPrecompetitive preclinical ADME/Tox data: set it free on the web to facilitate computational model building and assist drug developmentEthnobotany as a pharmacological research tool and recent developments in CNS-active natural products from ethnobotanical sources.PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptorsScreening the receptorome.A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanizationAntipsychotic medications and stroke in schizophrenia: A case-crossover study.Dopamine and serotonin receptor binding and antipsychotic efficacy.Analysis of multiple compound-protein interactions reveals novel bioactive moleculesEffect of paliperidone and risperidone on extracellular glutamate in the prefrontal cortex of rats exposed to prenatal immune activation or MK-801.Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activationReflections on the theory of "silver bullet" octreotide tracers: implications for ligand-receptor interactions in the age of peptides, heterodimers, receptor mosaics, truncated receptors, and multifractal analysis.Typical and atypical antipsychotic drugs increase extracellular histamine levels in the rat medial prefrontal cortex: contribution of histamine h(1) receptor blockadeIn silico pharmacology for drug discovery: applications to targets and beyondBack to the Roots: Prediction of Biologically Active Natural Products from Ayurveda Traditional Medicine.GLIDA: GPCR--ligand database for chemical genomics drug discovery--database and tools updateChemProt-2.0: visual navigation in a disease chemical biology databaseChemProt-3.0: a global chemical biology diseases mapping.Tetrahydroprotoberberine alkaloids with dopamine and σ receptor affinity.Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen.Trazodone: properties and utility in multiple disorders.A generalizable pre-clinical research approach for orphan disease therapyMolecular Signaling Pathways Behind the Biological Effects of Salvia Species Diterpenes in Neuropharmacology and Cardiology.Evidence for phosphatase activity of p27SJ and its impact on the cell cycle.p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death.Experimental models for anxiolytic drug discovery in the era of omes and omics.Screening of Hallucinogenic Compounds and Genomic Characterisation of 40 Anatolian Salvia Species.A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?D2 and D3 dopamine receptor affinity predicts effectiveness of antipsychotic drugs in obsessive-compulsive disorders: a metaregression analysisSalvia divinorum: toxicological aspects and analysis in human biological specimens
P2860
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P2860
Screening the receptorome to discover the molecular targets for plant-derived psychoactive compounds: a novel approach for CNS drug discovery.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Screening the receptorome to d ...... proach for CNS drug discovery.
@ast
Screening the receptorome to d ...... proach for CNS drug discovery.
@en
type
label
Screening the receptorome to d ...... proach for CNS drug discovery.
@ast
Screening the receptorome to d ...... proach for CNS drug discovery.
@en
prefLabel
Screening the receptorome to d ...... proach for CNS drug discovery.
@ast
Screening the receptorome to d ...... proach for CNS drug discovery.
@en
P2093
P1476
Screening the receptorome to d ...... proach for CNS drug discovery.
@en
P2093
Bryan L Roth
Estela Lopez
Jon M Evans
Richard B Westkaemper
Scott Beischel
P304
P356
10.1016/J.PHARMTHERA.2004.03.004
P577
2004-05-01T00:00:00Z