Decreased osteoclastogenesis in serotonin-deficient mice. - Wikidata - wikimedia - TriplyDB

Decreased osteoclastogenesis in serotonin-deficient mice.

Decreased osteoclastogenesis in serotonin-deficient mice.

http://www.wikidata.org/entity/Q35787005

about

Polymerase ε1 mutation in a human syndrome with facial dysmorphism, immunodeficiency, livedo, and short stature ("FILS syndrome")FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin 5-Hydroxytryptamine (serotonin) in the gastrointestinal tract Escherichia coli Nissle 1917 enhances bioavailability of serotonin in gut tissues through modulation of synthesis and clearance.Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology Physical weight loading induces expression of tryptophan hydroxylase 2 in the brain stem Elevated TNFR1 and serotonin in bone metastasis are correlated with poor survival following bone metastasis diagnosis for both carcinoma and sarcoma primary tumors.PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolism Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells.Serotonin signalling in the gut--functions, dysfunctions and therapeutic targets.Serotonin regulates calcium homeostasis in lactation by epigenetic activation of hedgehog signaling.Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression.Do Selective Serotonin Reuptake Inhibitors (SSRIs) Cause Fractures?Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis.Transcriptomic Analysis of the Mouse Mammary Gland Reveals New Insights for the Role of Serotonin in Lactation.Adult Tph2 knockout mice without brain serotonin have moderately elevated spine trabecular bone but moderately low cortical bone thickness Constitutively Elevated Blood Serotonin Is Associated with Bone Loss and Type 2 Diabetes in Rats.Life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks.Circulating serotonin and bone density, structure, and turnover in carcinoid syndrome Serotonin: good or bad for bone.PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease.Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.Gut microbiota induce IGF-1 and promote bone formation and growth.Effect of whole body vibration therapy on circulating serotonin levels in an ovariectomized rat model of osteoporosis.Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid.Signaling pathways affecting skeletal health.3-D imaging and illustration of mouse intestinal neurovascular complex.The roles of peripheral serotonin in metabolic homeostasis.Antagonism of serotonin receptor 1B decreases viability and promotes apoptosis in the COS canine osteosarcoma cell line.Tyrosine and tryptophan hydroxylases as therapeutic targets in human disease.Non-conventional features of peripheral serotonin signalling - the gut and beyond.Gut Microbiome and Bone: to Build, Destroy, or Both?Are serotonin metabolite levels related to bone mineral density in patients with neuroendocrine tumours?Oxidation of high doses of serotonin favors lipid accumulation in mouse and human fat cells.Serum serotonin concentration associated with bone mineral density in Chinese postmenopausal women.Dietary tryptophan manipulation reveals a central role for serotonin in the anabolic response of appendicular skeleton to physical activity in rats.Gender-specific risk factors for low bone mineral density in patients taking antipsychotics for psychosis.Regulation of Bone Metabolism by Serotonin.Metabolomics Based Profiling of Dexamethasone Side Effects in Rats.Mechanisms of gut microbiota-mediated bone remodeling.

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P2860

Decreased osteoclastogenesis in serotonin-deficient mice.

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Decreased osteoclastogenesis in serotonin-deficient mice.

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Decreased osteoclastogenesis in serotonin-deficient mice.

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Decreased osteoclastogenesis in serotonin-deficient mice.

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Decreased osteoclastogenesis in serotonin-deficient mice.

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Decreased osteoclastogenesis in serotonin-deficient mice.

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Amélie E Coudert

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Francine Côté

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Jacques Callebert

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Marie-Christine de Vernejoul

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Valérie Geoffroy

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Yasmine Chabbi-Achengli

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P2860

Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation

Lrp5 functions in bone to regulate bone mass

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum

Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function

Bone resorption by osteoclasts

5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes

Synthesis of serotonin by a second tryptophan hydroxylase isoform

Serotonin regulates mammary gland development via an autocrine-paracrine loop

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

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