Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue.
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Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channelExpression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney developmentA polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesEffect of hydro-osmotic pressure on polycystin-2 channel function in the human syncytiotrophoblastCiliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascadesA polycystin-centric view of cyst formation and disease: the polycystins revisitedPkd1 and Pkd2 are required for normal placental developmentMutations of the human polycystic kidney disease 2 (PKD2) geneRegulation of calcium signaling by polycystin-2Nek8 regulates the expression and localization of polycystin-1 and polycystin-2Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complexThe cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel FunctionPkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes.Polycystin-1 interacts with intermediate filaments.Double immunofluorescence labelling of routinely processed paraffin sections.Exon sequencing of PKD1 gene in an Iranian patient with autosomal-dominant polycystic kidney disease.Polycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.A loss-of-function model for cystogenesis in human autosomal dominant polycystic kidney disease type 2.Protein kinase D-mediated phosphorylation of polycystin-2 (TRPP2) is essential for its effects on cell growth and calcium channel activity.Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.Structural interaction and functional regulation of polycystin-2 by filaminKidney: polycystic kidney disease.Dysplastic and polycystic kidneys: diagnosis, associations and management.A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1Molecular mechanisms of renal development.Filamin-a increases the stability and plasma membrane expression of polycystin-2.Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney diseaseSubcellular localization and trafficking of polycystins.Pkd2 mesenteric vessels exhibit a primary defect in endothelium-dependent vasodilatation restored by rosiglitazone.Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling.The subcellular localization of TRPP2 modulates its function.Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system.Cyst formation in kidney via B-Raf signaling in the PKD2 transgenic mice.Ciliary dysfunction in polycystic kidney disease: an emerging model with polarizing potentialPkd2 dosage influences cellular repair responses following ischemia-reperfusion injury.Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD.Angiogenesis and autosomal dominant polycystic kidney disease.Metabolic abnormalities in autosomal dominant polycystic kidney disease.Imbalance and dysfunction of transient receptor potential channels contribute to the pathogenesis of hypertension.Haploinsufficiency of Pkd2 is associated with increased tubular cell proliferation and interstitial fibrosis in two murine Pkd2 models.
P2860
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P2860
Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Coordinate expression of the a ...... , in normal and cystic tissue.
@ast
Coordinate expression of the a ...... , in normal and cystic tissue.
@en
type
label
Coordinate expression of the a ...... , in normal and cystic tissue.
@ast
Coordinate expression of the a ...... , in normal and cystic tissue.
@en
prefLabel
Coordinate expression of the a ...... , in normal and cystic tissue.
@ast
Coordinate expression of the a ...... , in normal and cystic tissue.
@en
P2093
P2860
P1476
Coordinate expression of the a ...... 1, in normal and cystic tissue
@en
P2093
P C Harris
R J Butler
S Biddolph
P2860
P304
P356
10.1016/S0002-9440(10)65428-4
P407
P50
P577
1999-06-01T00:00:00Z