Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation.
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The notch ligand JAGGED1 as a target for anti-tumor therapyMain roads to melanomaPapillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activationThe haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell lineNotch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinasesIs there a role for Notch signalling in human breast cancer?Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null miceThe Role of HPV in Head and Neck Cancer Stem Cell Formation and TumorigenesisNotch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrityNrf2 and Notch Signaling in Lung Cancer: Near the CrossroadNickel-induced down-regulation of ΔNp63 and its role in the proliferation of keratinocytesNotch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomasCross-regulation between Notch and p63 in keratinocyte commitment to differentiationPresenilins regulate alphabeta T cell development by modulating TCR signalingABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signalingEvidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma.Notch1 activation is a poor prognostic factor in patients with gastric cancer.Notch is a critical regulator in cervical cancer by regulating Numb splicing.Clinical update on cancer: molecular oncology of head and neck cancerClinical impact of de-regulated Notch-1 and Notch-3 in the development and progression of HPV-associated different histological subtypes of precancerous and cancerous lesions of human uterine cervix.Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytes.Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation.Characterization of an atypical gamma-secretase complex from hematopoietic originDisruption of HPV16-E7 by CRISPR/Cas system induces apoptosis and growth inhibition in HPV16 positive human cervical cancer cellsActivation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression.Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras.NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinomaNovel approaches in anaplastic thyroid cancer therapyNotch3 and HEY-1 as prognostic biomarkers in pancreatic adenocarcinoma.Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells.Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancerNotch signaling proteins: legitimate targets for cancer therapy.Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway.Human papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrestCleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features.Notch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice.Tissue-specific alterations of PRL-1 and PRL-2 expression in cancerOverexpression of Notch1 is associated with the progression of cervical cancer.Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics.
P2860
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P2860
Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Specific down-modulation of No ...... s of malignant transformation.
@ast
Specific down-modulation of No ...... s of malignant transformation.
@en
type
label
Specific down-modulation of No ...... s of malignant transformation.
@ast
Specific down-modulation of No ...... s of malignant transformation.
@en
prefLabel
Specific down-modulation of No ...... s of malignant transformation.
@ast
Specific down-modulation of No ...... s of malignant transformation.
@en
P2093
P2860
P356
P1433
P1476
Specific down-modulation of No ...... s of malignant transformation.
@en
P2093
Christopher P Crum
Claudio Talora
Dennis C Sgroi
G Paolo Dotto
P2860
P304
P356
10.1101/GAD.988902
P577
2002-09-01T00:00:00Z