Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults. - Wikidata - wikimedia - TriplyDB

Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults.

Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults.

http://www.wikidata.org/entity/Q35787932

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Alzheimer mechanisms and therapeutic strategies Intrinsic patterns of coupling between correlation and amplitude of low-frequency fMRI fluctuations are disrupted in degenerative dementia mainly due to functional disconnection Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3.Why looking at the whole hippocampus is not enough-a critical role for anteroposterior axis, subfield and activation analyses to enhance predictive value of hippocampal changes for Alzheimer's disease diagnosis.Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly.Regional brain stiffness changes across the Alzheimer's disease spectrum Review of overlap between thermoregulation and pain modulation in fibromyalgia.Seizures and epileptiform activity in the early stages of Alzheimer disease Mapping the effect of the apolipoprotein E genotype on 4-year atrophy rates in an Alzheimer disease-related brain network Mild Cognitive Impairment Is Not "Mild" at All in Altered Activation of Episodic Memory Brain Networks: Evidence from ALE Meta-Analysis.Advances in MRI biomarkers for the diagnosis of Alzheimer's disease.Recent imaging advances in neurology.A comparison of FreeSurfer-generated data with and without manual intervention.Activity dependent degeneration explains hub vulnerability in Alzheimer's disease.Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease.New insights on the role of microglia in synaptic pruning in health and disease Functional MRI of mnemonic networks across the spectrum of normal aging, mild cognitive impairment, and Alzheimer's disease Insulin resistance in Alzheimer's disease.Aberrant functional organization within and between resting-state networks in AD The evolution of preclinical Alzheimer's disease: implications for prevention trials.Pattern separation and pattern completion in Alzheimer's disease: evidence of rapid forgetting in amnestic mild cognitive impairment.Brain amyloid-β burden is associated with disruption of intrinsic functional connectivity within the medial temporal lobe in cognitively normal elderly Using regional homogeneity to reveal altered spontaneous activity in patients with mild cognitive impairment Altered causal connectivity of resting state brain networks in amnesic MCI Imaging biomarkers associated with cognitive decline: a review.Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance Linking aβ42-induced hyperexcitability to neurodegeneration, learning and motor deficits, and a shorter lifespan in an Alzheimer's model Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression Opportunities and Limitations of Modelling Alzheimer's Disease with Induced Pluripotent Stem Cells Neuroanatomical Correlates of Recognizing Face Expressions in Mild Stages of Alzheimer's Disease.Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment.Impact of negative emotion on the neural correlates of long-term recognition in younger and older adults Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ1-42.Hippocampal oscillatory activity in Alzheimer's disease: toward the identification of early biomarkers?The parahippocampal gyrus links the default-mode cortical network with the medial temporal lobe memory system.Expression of Phenotypic Astrocyte Marker Is Increased in a Transgenic Mouse Model of Alzheimer's Disease versus Age-Matched Controls: A Presymptomatic Stage Study.Effects of the BDNF Val66Met polymorphism and met allele load on declarative memory related neural networks.

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Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults.

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Caroline Sullivan

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Deepti Putcha

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P2860

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

Neurodegenerative diseases target large-scale human brain networks

Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory

The Clinical Dementia Rating (CDR): current version and scoring rules

Resting-state functional connectivity reflects structural connectivity in the default mode network

Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

Disruption of functional connectivity in clinically normal older adults harboring amyloid burden.

Mild cognitive impairment: evaluation with 4-T functional MR imaging.

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