Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment.
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Pathophysiological power of improper tonic GABA(A) conductances in mature and immature models.Molecular aspects of age-related cognitive decline: the role of GABA signalingParvalbumin and neuropeptide Y expressing hippocampal GABA-ergic inhibitory interneuron numbers decline in a model of Gulf War illnessAllosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].Reassessing the effects of histone deacetylase inhibitors on hippocampal memory and cognitive aging.Global view of transcriptome in the brains of aged NR2B transgenic miceEster to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit.Neurosteroid biosynthesis downregulation and changes in GABAA receptor subunit composition: A biomarker axis in stress-induced cognitive and emotional impairment.Behaviorally activated mRNA expression profiles produce signatures of learning and enhanced inhibition in aged rats with preserved memory.Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performanceAssociation of Pancreatic Polypeptide with Mild Cognitive Impairment Varies by APOE ε4 Allele.Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex.Age-associated changes in hippocampal-dependent cognition in Diversity Outbred miceHilar interneuron vulnerability distinguishes aged rats with memory impairment.Memory impairment in aged primates is associated with region-specific network dysfunction.α5GABAA receptor deficiency causes autism-like behaviorsSex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator.Disinhibition, an emerging pharmacology of learning and memoryCognition-impairing effects of benzodiazepine-type drugs: role of GABAA receptor subtypes in an executive function task in rhesus monkeysSh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects.Benzodiazepine receptor ligands: a patent review (2006-2012).Cognitive deficits caused by prefrontal cortical and hippocampal neural disinhibition.Targeting Neural Hyperactivity as a Treatment to Stem Progression of Late-Onset Alzheimer's Disease.α7-nAChR agonist enhances neural plasticity in the hippocampus via a GABAergic circuit.Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats.Antiaging and Anxiolytic Effects of Combinatory Formulas Based on Four Medicinal Herbs.Combined administration of levetiracetam and valproic acid attenuates age-related hyperactivity of CA3 place cells, reduces place field area, and increases spatial information content in aged rat hippocampus.Marked bias towards spontaneous synaptic inhibition distinguishes non-adapting from adapting layer 5 pyramidal neurons in the barrel cortex.Heightened cortical excitability in aged rodents with memory impairment.Spatial recognition test: A novel cognition task for assessing topographical memory in mice.Treatment with levetiracetam improves cognition in a ketamine rat model of schizophrenia.[Mechanisms of Alzheimer's disease : Neuronal hyperactivity and hypoactivity as new therapeutic targets].
P2860
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P2860
Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Selective GABA(A) α5 positive ...... d rats with memory impairment.
@ast
Selective GABA(A) α5 positive ...... d rats with memory impairment.
@en
type
label
Selective GABA(A) α5 positive ...... d rats with memory impairment.
@ast
Selective GABA(A) α5 positive ...... d rats with memory impairment.
@en
prefLabel
Selective GABA(A) α5 positive ...... d rats with memory impairment.
@ast
Selective GABA(A) α5 positive ...... d rats with memory impairment.
@en
P2093
P2860
P1433
P1476
Selective GABA(A) α5 positive ...... d rats with memory impairment.
@en
P2093
Michela Gallagher
Ming Teng Koh
Sharon Rosenzweig-Lipson
P2860
P304
P356
10.1016/J.NEUROPHARM.2012.06.023
P577
2012-06-23T00:00:00Z