Megalin knockout mice as an animal model of low molecular weight proteinuria. - Wikidata - wikimedia - TriplyDB

Megalin knockout mice as an animal model of low molecular weight proteinuria.

Megalin knockout mice as an animal model of low molecular weight proteinuria.

http://www.wikidata.org/entity/Q35788270

about

AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2 Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding Megalin in acute kidney injury: foe and friend The cellular and physiological functions of the Lowe syndrome protein OCRL1 Podocyte endocytosis in the regulation of the glomerular filtration barrier Inositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathies Megalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal function Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex Antisense down-regulation of lipocalin-interacting membrane receptor expression inhibits cellular internalization of lipocalin-1 in human NT2 cells Molecular cloning of a novel lipocalin-1 interacting human cell membrane receptor using phage display Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2 The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles Loss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiation Age-related change of endocytic receptors megalin and cubilin in the kidney in rats The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN.Phosphotriesterase-related protein sensed albuminuria and conferred renal tubular cell activation in membranous nephropathy.Time course of pathogenic and adaptation mechanisms in cystinotic mouse kidneys Ectopic germinal center and megalin defect in primary Sjogren syndrome with renal Fanconi syndrome.Lipoprotein receptors: new roles for ancient proteins.Rediscovering Beta-2 Microglobulin As a Biomarker across the Spectrum of Kidney Diseases.Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2.Protective effect of resin adsorption on septic plasma-induced tubular injury.Luminal Na(+)/H (+) exchange in the proximal tubule Mechanisms of AT1a receptor-mediated uptake of angiotensin II by proximal tubule cells: a novel role of the multiligand endocytic receptor megalin.A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis.Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule.Rat enterocytes secrete SLPs containing alkaline phosphatase and cubilin in response to corn oil feeding.Transcobalamin II receptor interacts with megalin in the renal apical brush border membrane.Cadmium impairs albumin reabsorption by down-regulating megalin and ClC5 channels in renal proximal tubule cells.Metabolism, energetics, and lipid biology in the podocyte - cellular cholesterol-mediated glomerular injury.The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins.Enhanced excretion of vitamin D binding protein in type 1 diabetes: a role in vitamin D deficiency?Urinary vitamin D binding protein: a potential novel marker of renal interstitial inflammation and fibrosis Tubular reabsorption and local production of urine hepcidin-25.

P2860

Q24296494-1A4F3566-D85D-4F8D-A07D-E68370B15F1C Q24534474-8348910F-25FE-47AB-9A82-D610545AD4BC Q24569564-4B605339-1B3F-465E-855A-AAF2D4C9E627 Q24629822-5EFAFF22-D7FD-4EB6-BCAB-C0CC7A850B2B Q24648224-EB36AB50-D149-4BC1-8C3E-416C089F9005 Q26823048-AEA24F17-3CA0-4EFF-8F43-B666F1B2110A Q26862286-E1E2F5EB-F9FD-47DE-9CE9-223FAF98763B Q27004073-E252FF30-6A9B-4A21-A8D0-4AFFDE4F832D Q27012842-9AE2AE3B-4C56-4F5C-BE2E-046F737A9DFB Q27437610-B93A648B-05F9-43C4-98A9-F150003BBE88 Q27662810-98EF2B32-59FC-49E5-8274-B1B89DE35506 Q28210393-A466751B-93B9-4EFC-8398-0BAB77BFF59D Q28210582-E9ECED05-97A1-4B35-A8A2-01A069EE59F8 Q28301617-88AC04AD-692E-4ECB-9AD6-DA37675EDFEB Q28307851-15980D20-9F9F-431C-814A-8E0563941713 Q28506913-78A972D5-7036-4016-9CDC-0C70F1C81023 Q28511953-D291C483-9BEC-44CD-BFFD-97E310BBB48A Q28566060-E2DDC3C9-9984-46BE-BBF7-DF4F21078876 Q28570698-2818C94B-8D80-43AB-8954-E900FA22AEB1 Q28577988-035E39DB-B686-4BCC-9C86-242B2C37C2AB Q33229789-051D8AB6-1AB1-4665-BBF1-0FC3AD238B9E Q33577283-BA141A5A-CC44-44A7-A1A3-89FC600F7A78 Q33660575-67EC10B7-6A70-4DC2-803E-EC4D86F13E3E Q33755913-3609C945-1937-4214-B4D3-01A03AA7E0D3 Q33772665-F417FB7B-B955-42C1-A995-F8660BC191D7 Q33799767-F1E7A82E-78B0-4FAF-810D-3843999BC97A Q33849227-8399F136-67E5-4168-A00A-3D96A1E9CF88 Q33873370-57E586A3-8E53-4C67-9B52-9C028355B731 Q33884278-2A5E5355-E7A9-4664-9E30-5AC3D4B76056 Q33913058-64268BCF-FE86-4216-B372-8E18A1D85253 Q34159448-D61AE9FE-10DF-4D04-A46D-814B8230A18D Q34183565-A1A78F71-0098-453C-A625-2D82A4D658D7 Q34186323-D22B545E-BE43-456F-A648-840678F8BD87 Q34216851-732895F8-6D65-4956-8237-FDC57AB2964B Q34282828-7283357F-B4AB-47B0-AAC6-B05F81BF3925 Q34336370-2F9A8AE0-D9A7-41D0-93A7-4174E88586EA Q34535813-3DF96512-888C-4C36-B0EA-972E71640DA7 Q34571836-1B36E23F-43DC-4FF3-A780-448AE2C51165 Q34586403-F0695BAA-AD04-4297-9548-9B7B3FABE2E3 Q34636734-E73F791D-EDBE-4551-964C-451F45D13ED8

P2860

Megalin knockout mice as an animal model of low molecular weight proteinuria.

http://www.wikidata.org/entity/Q35788270

description

1999 nî lūn-bûn

@nan

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

1999年论文

@zh

1999年论文

@zh-cn

name

Megalin knockout mice as an animal model of low molecular weight proteinuria.

@ast

Megalin knockout mice as an animal model of low molecular weight proteinuria.

@en

type

label

Megalin knockout mice as an animal model of low molecular weight proteinuria.

@ast

Megalin knockout mice as an animal model of low molecular weight proteinuria.

@en

prefLabel

Megalin knockout mice as an animal model of low molecular weight proteinuria.

@ast

Megalin knockout mice as an animal model of low molecular weight proteinuria.

@en

P1433

Q35788270-2E77FC46-C8F7-466B-B5A9-8A9D1B246AB2

P1476

Q35788270-34F29F32-B8CC-4FCD-9D07-662D0EBA9392

P2093

Q35788270-30FE1656-A1C2-4B0A-9D08-746D02ED08C6

Q35788270-46ECDB3D-12D4-4A18-81BB-56CB84D21EC8

Q35788270-5C368B37-97E8-4217-B436-76AC5830B530

Q35788270-A22F7917-D1BF-479E-B815-93E71D6508A6

Q35788270-A9B63BD4-06D5-49A8-910A-56C2F4A01031

Q35788270-AFD50E47-ECCA-4D9C-A6C7-E865E01C8DA7

Q35788270-B4795A31-8259-4ABC-87BD-5BEA14C33186

Q35788270-DBAAE7BF-129C-4B0A-B40A-D024E7013182

Q35788270-EB660D0B-51CF-40F6-B084-F2DA32FD845B

P2860

Q35788270-058EAD4F-A4EE-4D77-91BF-A7D8BE1DD476

Q35788270-0F09DE9B-F42C-4D3E-9060-7647F53FF16A

Q35788270-16E6C0AB-A384-4CB7-AE48-C9853C11E0ED

Q35788270-23252C58-C95D-4EA7-8EDD-D1A8AD28C371

Q35788270-2437124B-26E4-40C2-8AC6-68A84F769A4A

Q35788270-25FA924C-7C65-4B8E-AE46-5133A75F0F42

Q35788270-31CE8B0D-BB26-4E92-8203-7308C25E9B98

Q35788270-3940ADB0-E24C-49C7-9DDA-0A250A258ADC

Q35788270-40500FCC-6C6B-45DA-9119-6B34C8730DF3

Q35788270-6480E0B3-88FA-40E9-9754-9F7AD2D181BB

P304

Q35788270-15820D8E-9C83-44D3-BD5A-0711ABAF2581

P31

Q35788270-A774346B-DA12-4846-9668-C3D936F08364

P356

Q35788270-2BC080FD-F7DF-4431-B287-8F3CE51CB378

P407

Q35788270-4B7F2D36-DEB0-4E42-8829-B80EB7144E76

P433

Q35788270-1F967680-7BF4-42E8-BA86-74E82D8B7140

P478

Q35788270-C2CDA126-630D-4D1A-8FF2-1E76523D89E8

P50

Q35788270-38549A5A-CF54-4971-9A69-B1756AFD26A5

Q35788270-B0CEC38C-D4F9-4CC6-BAA2-7C4E120305AC

P577

Q35788270-D074CDD3-45E5-4F77-A7AA-C24DCD51A6AD

P5875

Q35788270-78801C15-F63F-4A59-AF02-6D9036C65994

P698

Q35788270-0A7F1D11-7BAE-41DC-9D1E-E10F28CB047F

P921

Q35788270-6C051397-01E0-486B-9B20-FDEDB7D49CD0

P932

Q35788270-A7F15086-1300-4F03-B445-F83B488271DE

P356

S0002-9440(10)65238-8

P1433

The American Journal of Pathology

P1476

Megalin knockout mice as an animal model of low molecular weight proteinuria

@en

P2093

A Otto

http://www.w3.org/2001/XMLSchema#string

B Rolinski

http://www.w3.org/2001/XMLSchema#string

C Jacobsen

http://www.w3.org/2001/XMLSchema#string

E I Christensen

http://www.w3.org/2001/XMLSchema#string

H Vorum

http://www.w3.org/2001/XMLSchema#string

J Hilpert

http://www.w3.org/2001/XMLSchema#string

J O Moskaug

http://www.w3.org/2001/XMLSchema#string

J R Leheste

http://www.w3.org/2001/XMLSchema#string

P Aucouturier

http://www.w3.org/2001/XMLSchema#string

P2860

Megalin is an endocytic receptor for insulin

The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins

Defective forebrain development in mice lacking gp330/megalin.

Evidence for an essential role of megalin in transepithelial transport of retinol

Molecular cloning of a cDNA encoding human calumenin, expression in Escherichia coli and analysis of its Ca2+-binding activity

An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3

Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril

Renal filtration, transport, and metabolism of low-molecular-weight proteins: a review.

Renal tubule gp330 is a calcium binding receptor for endocytic uptake of protein.

P304

1361-1370

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/S0002-9440(10)65238-8

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

155

http://www.w3.org/2001/XMLSchema#string

P50

Thomas E Willnow

P577

1999-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

25607358

http://www.w3.org/2001/XMLSchema#string

P698

10514418

http://www.w3.org/2001/XMLSchema#string

P921

P932

1867027

http://www.w3.org/2001/XMLSchema#string