Glucose- and hormone-induced cAMP oscillations in α- and β-cells within intact pancreatic islets.
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CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cellsCyclic AMP dynamics in the pancreatic β-cellGlucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cellsAnchored phosphatases modulate glucose homeostasisLipotoxicity disrupts incretin-regulated human β cell connectivityIncretin-modulated beta cell energetics in intact islets of Langerhans.Activation of GPR40 attenuates chronic inflammation induced impact on pancreatic β-cells health and function.cAMP induces stromal interaction molecule 1 (STIM1) puncta but neither Orai1 protein clustering nor store-operated Ca2+ entry (SOCE) in islet cells.Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca2+ in female mouse islets stimulated by glucose and tolbutamide.Soluble adenylyl cyclase in health and disease.Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMPChronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (α-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cellsThe soluble guanylyl cyclase activator YC-1 increases intracellular cGMP and cAMP via independent mechanisms in INS-1E cellsRp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion.Effect of glucagon on insulin secretion through cAMP signaling pathway in MIN6 cellsModeling of glucose-induced cAMP oscillations in pancreatic β cells: cAMP rocks when metabolism rollsTranscriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.A computational systems analysis of factors regulating α cell glucagon secretion.Glucagon regulates its own synthesis by autocrine signaling.High glucose and free fatty acids induce beta cell apoptosis via autocrine effects of ADP acting on the P2Y(13) receptor.Oscillations of sub-membrane ATP in glucose-stimulated beta cells depend on negative feedback from Ca(2+).X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function.Fluorescent protein vectors for pancreatic islet cell identification in live-cell imaging.Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensorPharmacological distinction between soluble and transmembrane adenylyl cyclases.New insights into the role of connexins in pancreatic islet function and diabetes.ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout miceAdenylate cyclase-centred microdomains.Glucose control of glucagon secretion-'There's a brand-new gimmick every year'.The Pancreatic β-Cell: A Bioenergetic Perspective.Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans.International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Inhibitory effect of zinc on glucose-stimulated zinc/insulin secretion in an insulin-secreting β-cell line.cAMP signalling in insulin and glucagon secretion.Protein Kinase A Governs Oxidative Phosphorylation Kinetics and Oxidant Emitting Potential at Complex I.Submembrane ATP and Ca2+ kinetics in α-cells: unexpected signaling for glucagon secretion.Autocrine effect of Zn²⁺ on the glucose-stimulated insulin secretion.Upregulation of an inward rectifying K+ channel can rescue slow Ca2+ oscillations in K(ATP) channel deficient pancreatic islets.
P2860
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P2860
Glucose- and hormone-induced cAMP oscillations in α- and β-cells within intact pancreatic islets.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Glucose- and hormone-induced c ...... thin intact pancreatic islets.
@ast
Glucose- and hormone-induced c ...... thin intact pancreatic islets.
@en
type
label
Glucose- and hormone-induced c ...... thin intact pancreatic islets.
@ast
Glucose- and hormone-induced c ...... thin intact pancreatic islets.
@en
prefLabel
Glucose- and hormone-induced c ...... thin intact pancreatic islets.
@ast
Glucose- and hormone-induced c ...... thin intact pancreatic islets.
@en
P2860
P356
P1433
P1476
Glucose- and hormone-induced c ...... thin intact pancreatic islets.
@en
P2093
Anders Tengholm
P2860
P304
P356
10.2337/DB10-1087
P407
P577
2011-03-28T00:00:00Z