PPARγ contributes to PKM2 and HK2 expression in fatty liver - Wikidata - wikimedia - TriplyDB

PPARγ contributes to PKM2 and HK2 expression in fatty liver

PPARγ contributes to PKM2 and HK2 expression in fatty liver

http://www.wikidata.org/entity/Q35801521

about

Pyruvate kinase M2 at a glance Heterogeneity of glycolysis in cancers and therapeutic opportunities.Role of PI3K, mTOR and Akt2 signalling in hepatic tumorigenesis via the control of PKM2 expression Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling.Vertical sleeve gastrectomy reverses diet-induced gene-regulatory changes impacting lipid metabolism Changes in nucleosome occupancy associated with metabolic alterations in aged mammalian liver.Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease.p63 supports aerobic respiration through hexokinase II.The combined deletion of S6K1 and Akt2 deteriorates glycemic control in a high-fat diet.Emerging roles of PKM2 in cell metabolism and cancer progression Nuclear receptors and the Warburg effect in cancer.Liver fatty acid binding protein (L-Fabp) modulates murine stellate cell activation and diet-induced nonalcoholic fatty liver disease.Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.Multivariate analysis and molecular interaction of curcumin with PPARγ in high fructose diet induced insulin resistance in rats.IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation.PPARs and Mitochondrial Metabolism: From NAFLD to HCC.Regulation and function of pyruvate kinase M2 in cancer.Hexokinase 2 enhances the metastatic potential of tongue squamous cell carcinoma via the SOD2-H2O2 pathway.Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4.Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPAR γ Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease.Dysregulated glycolysis as an oncogenic event.Glycolytic enzymes PGK1 and PKM2 as novel transcriptional targets of PPARγ in breast cancer pathophysiology.Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor Inhibition of glucose-transporter 1 (GLUT-1) expression reversed Warburg effect in gastric cancer cell MKN45.Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.Metabolic Reprogramming, Autophagy, and Reactive Oxygen Species Are Necessary for Primordial Germ Cell Reprogramming into Pluripotency.Splicing regulator SLU7 is essential for maintaining liver homeostasis.Prolonged fasting elicits increased hepatic triglyceride accumulation in rats born to dexamethasone-treated mothers.Pyruvate kinase M2 deregulation enhances the metastatic potential of tongue squamous cell carcinoma.STAT6 promotes bi-directional modulation of PKM2 in liver and adipose inflammatory cells in rosiglitazone-treated mice.Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription.Serum and Liver Tissue Metabonomic Study on Fatty Liver in Rats Induced by High-Fat Diet and Intervention Effects of Traditional Chinese Medicine Qushi Huayu Decoction.Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation Naringenin attenuates hepatitis B virus X protein-induced hepatic steatosis.BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells.Hexokinase II in breast carcinoma: a potent prognostic factor associated with hypoxia-inducible factor-1α and Ki-67.Posttranslational Modifications of Pyruvate Kinase M2: Tweaks that Benefit Cancer.LY294002 inhibits the Warburg effect in gastric cancer cells by downregulating pyruvate kinase M2.

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PPARγ contributes to PKM2 and HK2 expression in fatty liver

http://www.wikidata.org/entity/Q35801521

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

@zh-tw

2012年论文

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2012年论文

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2012年论文

@zh-cn

name

PPARγ contributes to PKM2 and HK2 expression in fatty liver

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PPARγ contributes to PKM2 and HK2 expression in fatty liver

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PPARγ contributes to PKM2 and HK2 expression in fatty liver

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PPARγ contributes to PKM2 and HK2 expression in fatty liver

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prefLabel

PPARγ contributes to PKM2 and HK2 expression in fatty liver

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PPARγ contributes to PKM2 and HK2 expression in fatty liver

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Nature Communications

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PPARγ contributes to PKM2 and HK2 expression in fatty liver

@en

P2093

Akira Suzuki

http://www.w3.org/2001/XMLSchema#string

Catherine Espeillac

http://www.w3.org/2001/XMLSchema#string

Céline Chauvin

http://www.w3.org/2001/XMLSchema#string

Ganna Panasyuk

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Jean-Ehrland Ricci

http://www.w3.org/2001/XMLSchema#string

Jean-Sebastien Annicotte

http://www.w3.org/2001/XMLSchema#string

Lluis Fajas

http://www.w3.org/2001/XMLSchema#string

Ludivine A Pradelli

http://www.w3.org/2001/XMLSchema#string

Marco Pontoglio

http://www.w3.org/2001/XMLSchema#string

Mario Pende

http://www.w3.org/2001/XMLSchema#string

P2860

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis

FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue

Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy

Pyruvate kinase M2 is a phosphotyrosine-binding protein

APC-dependent suppression of colon carcinogenesis by PPARgamma

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

Fat and beyond: the diverse biology of PPARgamma

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

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672

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10.1038/NCOMMS1667

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P478

3

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Morris J. Birnbaum

Jean-Yves Scoazec

Francisco Verdeguer

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2012-02-14T00:00:00Z

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221832131

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1025863486

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22334075

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3293420

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