Lost in translation: dysregulation of cap-dependent translation and cancer.
about
4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferationDietary interventions to extend life span and health span based on calorie restrictionThe mTOR signalling pathway in human cancerAmino acid management in cancerFrom scourge to cure: tumour-selective viral pathogenesis as a new strategy against cancerDiverse mechanisms of AKT pathway activation in human malignancyCell-specific monitoring of protein synthesis in vivoFlavivirus Activates Phosphatidylinositol 3-Kinase Signaling To Block Caspase-Dependent Apoptotic Cell Death at the Early Stage of Virus InfectionTOR signaling is a determinant of cell survival in response to DNA damage.Computational modeling and analysis of insulin induced eukaryotic translation initiationRapamycin inhibits IGF-1-mediated up-regulation of MDM2 and sensitizes cancer cells to chemotherapyIdentification and functional characterization of the candidate tumor suppressor gene TRIT1 in human lung cancer.Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1.Evaluation of everolimus in renal cell cancer.Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden.Enhancing mTOR-targeted cancer therapy.Maintaining glycogen synthase kinase-3 activity is critical for mTOR kinase inhibitors to inhibit cancer cell growth.Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP.Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.Deregulation of eIF4E: 4E-BP1 in differentiated human papillomavirus-containing cells leads to high levels of expression of the E7 oncoprotein.High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR SignalingGSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growthInhibitors of the mammalian target of rapamycin.The gene encoding the splicing factor SF2/ASF is a proto-oncogeneAutophagy in metazoans: cell survival in the land of plenty.Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cellsInhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylationOpposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancyInhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest.Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells.Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody.Coordination of Ribosomal Protein and Ribosomal RNA Gene Expression in Response to TOR Signaling.Insulin augments gonadotropin-releasing hormone induction of translation in LbetaT2 cells.Small-Molecule targeting of translation initiation for cancer therapy.ER stress inducer tunicamycin suppresses the self-renewal of glioma-initiating cell partly through inhibiting Sox2 translation.tRNA over-expression in breast cancer and functional consequences.Translation initiation: a critical signalling node in cancer.Protein Synthesis Rate Assessment by Fluorescence Recovery after Photobleaching (FRAP).
P2860
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P2860
Lost in translation: dysregulation of cap-dependent translation and cancer.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Lost in translation: dysregulation of cap-dependent translation and cancer.
@ast
Lost in translation: dysregulation of cap-dependent translation and cancer.
@en
type
label
Lost in translation: dysregulation of cap-dependent translation and cancer.
@ast
Lost in translation: dysregulation of cap-dependent translation and cancer.
@en
prefLabel
Lost in translation: dysregulation of cap-dependent translation and cancer.
@ast
Lost in translation: dysregulation of cap-dependent translation and cancer.
@en
P1433
P1476
Lost in translation: dysregulation of cap-dependent translation and cancer.
@en
P2093
Mary-Ann Bjornsti
Peter J Houghton
P304
P356
10.1016/J.CCR.2004.05.027
P577
2004-06-01T00:00:00Z