Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity.
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A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responsesAsymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein BThe virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells.Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative womenNasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization.Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.Specificities of human CD4+ T cell responses to an inactivated flavivirus vaccine and infection: correlation with structure and epitope predictionTh-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection.CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination.Broad and cross-clade CD4+ T-cell responses elicited by a DNA vaccine encoding highly conserved and promiscuous HIV-1 M-group consensus peptides.In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitizPhenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpesAlterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge.The Role of Plasmacytoid Dendritic Cells in Innate and Adaptive Immune Responses against Alpha Herpes Virus InfectionsImmunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjects.Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individualsDiscovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling.A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challengeDeveloping an asymptomatic mucosal herpes vaccine: the present and the future.Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex VaccineProspects for developing an effective vaccine against ocular herpes simplex virus infection.Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2.CD4 T cell responses in latent and chronic viral infections.Gender-dependent HLA-DR-restricted epitopes identified from herpes simplex virus type 1 glycoprotein D.Effector CD4+ T-cell involvement in clearance of infectious herpes simplex virus type 1 from sensory ganglia and spinal cordsImmune responses of mice with different genetic backgrounds to improved multiepitope, multitarget malaria vaccine candidate antigen FALVAC-1A.Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeuticsA novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes.Vaxfectin-adjuvanted plasmid DNA vaccine improves protection and immunogenicity in a murine model of genital herpes infectionPotent adjuvant activity of cationic liposome-DNA complexes for genital herpes vaccinesDendritic cell-based vaccines in treating recurrent herpes labialis: Results of pilot clinical study.Immunology in the Clinic Review Series; focus on host responses: T cell responses to herpes simplex viruses.Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines.Activation of monocytic cells by immunostimulatory lipids conjugated to peptide antigens.Long-term multiepitopic cytotoxic-T-lymphocyte responses induced in chimpanzees by combinations of Plasmodium falciparum liver-stage peptides and lipopeptides.Differential expression of mRNA and miRNA in guinea pigs following infection with HSV2v.In silico prediction and immunological validation of common HLA-DRB1-restricted T cell epitopes of Candida albicans secretory aspartyl proteinase 2.Laser Adjuvant-Assisted Peptide Vaccine Promotes Skin Mobilization of Dendritic Cells and Enhances Protective CD8+ TEM and TRM Cell Responses Against Herpes Infection and Disease‡.
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P2860
Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Identification of novel immuno ...... at confer protective immunity.
@ast
Identification of novel immuno ...... at confer protective immunity.
@en
type
label
Identification of novel immuno ...... at confer protective immunity.
@ast
Identification of novel immuno ...... at confer protective immunity.
@en
prefLabel
Identification of novel immuno ...... at confer protective immunity.
@ast
Identification of novel immuno ...... at confer protective immunity.
@en
P2093
P2860
P1433
P1476
Identification of novel immuno ...... at confer protective immunity.
@en
P2093
Anthony B Nesburn
Cory D McNamara
Georges Bertrand
Helene Gras-Masse
Juergen Hammer
Lbachir BenMohamed
Steven L Wechsler
P2860
P304
P356
10.1128/JVI.77.17.9463-9473.2003
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P577
2003-09-01T00:00:00Z