IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload.
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Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and DiseaseKeep your heart in shape: molecular chaperone networks for treating heart diseaseThe biology of IQGAP proteins: beyond the cytoskeletonMelusin Promotes a Protective Signal Transduction Cascade in Stressed HeartsIQGAP1 mediates angiotensin II-induced apoptosis of podocytes via the ERK1/2 MAPK signaling pathwayHierarchical scaffolding of an ERK1/2 activation pathwayIQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway.Targeted deletion of ERK2 in cardiomyocytes attenuates hypertrophic response but provokes pathological stress induced cardiac dysfunction.Effects of late administration of pentoxifylline and tocotrienols in an image-guided rat model of localized heart irradiationMechanical stress triggers cardiomyocyte autophagy through angiotensin II type 1 receptor-mediated p38MAP kinase independently of angiotensin II.Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes.IQGAPs choreograph cellular signaling from the membrane to the nucleusIQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice.IQGAP1 and its binding proteins control diverse biological functions.A conserved role of IQGAP1 in regulating TOR complex 1Watch the GAP: Emerging Roles for IQ Motif-Containing GTPase-Activating Proteins IQGAPs in Hepatocellular CarcinomaInhibition of G-protein-coupled receptor kinase 2 (GRK2) triggers the growth-promoting mitogen-activated protein kinase (MAPK) pathway.ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1Inhibition of farnesyl pyrophosphate synthase improves pressure overload induced chronic cardiac remodelingIQGAP1: a regulator of intracellular spacetime relativity.Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount.Key role of ERK1/2 molecular scaffolds in heart pathology.A molecular rheostat at the interface of cancer and diabetesHeart failure-specific changes in protein kinase signalling.The muscle-specific chaperone protein melusin is a potent cardioprotective agent.IQGAP1: insights into the function of a molecular puppeteer.IQGAP1 is a phosphoinositide effector and kinase scaffoldCirculating mRNA in Maternal Plasma at the Second Trimester of Pregnancy: A Possible Screening Tool for Cardiac Conotruncal and Left Ventricular Outflow Tract Abnormalities.Absence of IQGAP1 Protein Leads to Insulin Resistance.Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity.BcIqg1, a fungal IQGAP homolog, interacts with NADPH oxidase, MAP kinase and calcium signaling proteins and regulates virulence and development in Botrytis cinerea.IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells.Protective Roles of Interferon-γ in Cardiac Hypertrophy Induced by Sustained Pressure Overload.Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis.Ras GTPase-Activating-Like Protein IQGAP1 (IQGAP1) Promotes Breast Cancer Proliferation and Invasion and Correlates with Poor Clinical Outcomes.IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells.
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P2860
IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
IQGAP1 regulates ERK1/2 and AK ...... elling upon pressure overload.
@ast
IQGAP1 regulates ERK1/2 and AK ...... elling upon pressure overload.
@en
type
label
IQGAP1 regulates ERK1/2 and AK ...... elling upon pressure overload.
@ast
IQGAP1 regulates ERK1/2 and AK ...... elling upon pressure overload.
@en
prefLabel
IQGAP1 regulates ERK1/2 and AK ...... elling upon pressure overload.
@ast
IQGAP1 regulates ERK1/2 and AK ...... elling upon pressure overload.
@en
P2093
P2860
P50
P356
P1476
IQGAP1 regulates ERK1/2 and AK ...... delling upon pressure overload
@en
P2093
Emanuele De Blasio
Emilia Turco
Lorenzo Silengo
Mara Brancaccio
Wadie F Bahou
P2860
P304
P356
10.1093/CVR/CVR103
P50
P577
2011-04-14T00:00:00Z