Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.
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Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217AImportant role of the cys-191 cys-220 disulfide bond in thrombin function and allosteryStructural identification of the pathway of long-range communication in an allosteric enzymeStabilization of the E* Form Turns Thrombin into an AnticoagulantRigidification of the autolysis loop enhances Na+ binding to thrombinRole of coagulation in the recruitment of colon adenocarcinoma cells to thrombus under shear.Thrombin mutant W215A/E217A treatment improves neurological outcome and reduces cerebral infarct size in a mouse model of ischemic stroke.Engineering thrombin for selective specificity toward protein C and PAR1.Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis.Redesigning allosteric activation in an enzyme.The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A.WEDGE: an anticoagulant thrombin mutant produced by autoactivation.Allostery in trypsin-like proteases suggests new therapeutic strategies.Safety and antithrombotic efficacy of moderate platelet count reduction by thrombopoietin inhibition in primates.Thrombin.Design of Factor XIII V34X activation peptides to control ability to interact with thrombin mutants.Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XIRecombinant human activated protein C: current insights into its mechanism of actionThe Yin-Yang of thrombin and activated protein C.Activated protein C in sepsis: the promise of nonanticoagulant activated protein C.Slow thrombin is zymogen-likeInhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking.Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates.
P2860
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P2860
Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Relative antithrombotic and an ...... ar-weight heparin in primates.
@ast
Relative antithrombotic and an ...... ar-weight heparin in primates.
@en
type
label
Relative antithrombotic and an ...... ar-weight heparin in primates.
@ast
Relative antithrombotic and an ...... ar-weight heparin in primates.
@en
prefLabel
Relative antithrombotic and an ...... ar-weight heparin in primates.
@ast
Relative antithrombotic and an ...... ar-weight heparin in primates.
@en
P2093
P2860
P1433
P1476
Relative antithrombotic and an ...... lar-weight heparin in primates
@en
P2093
Enrico Di Cera
Erik I Tucker
John H Griffin
José A Fernández
Leslie Bush
Michelle A Berny
Owen J T McCarty
Stephen R Hanson
Ulla M Marzec
P2860
P304
P356
10.1182/BLOOD-2006-07-035147
P407
P577
2007-01-16T00:00:00Z